Clin Chem Lab Med. 2026 May 20. doi: 10.1515/cclm-2026-0553. Online ahead of print. ABSTRACT OBJECTIVES: Hereditary transthyretin amyloidosis (ATTRv) is a rare autosomal dominant disorder caused by pathogenic variants in the TTR gene, with marked clinical heterogeneity and frequent underdiagnosis. Genetic confirmation is essential for patient management but is traditionally based on Sanger sequencing or … Read more
Clin Chem Lab Med. 2026 May 19. doi: 10.1515/cclm-2026-0382. Online ahead of print. ABSTRACT OBJECTIVES: The 20- and 22-kDa isoforms of growth hormone 1 (GH1) play potentially distinct physiological and pathological roles, but their structural similarity makes quantification challenging. Conventional immunoassays lack sufficient specificity, highlighting the need for more precise analytical methods. METHODS: We developed … Read more
Clin Chem Lab Med. 2026 May 19. doi: 10.1515/cclm-2026-0276. Online ahead of print. ABSTRACT OBJECTIVES: A major objective of the IFCC Committee for Education in the Use of Biomarkers in Diabetes is to monitor the success of global standardization of HbA1c through benchmark evaluation of the performance by country and manufacturer. METHODS: From 2016 to … Read more
Clin Chem Lab Med. 2026 May 15. doi: 10.1515/cclm-2026-0179. Online ahead of print. ABSTRACT OBJECTIVES: Myositis specific antibodies (MSA) are important in the diagnosis of idiopathic inflammatory myopathies (IIM). In addition, several studies have shown clear utility to stratify IIM patients into more homogeneous subsets based on MSA signatures. However, methods for MSA detection show … Read more
Clin Chem Lab Med. 2026 May 15. doi: 10.1515/cclm-2026-0388. Online ahead of print. ABSTRACT OBJECTIVES: This study aimed to calculate the measurement uncertainty (MU) of HbA1c and glucose according to ISO/TS 20914:2019 guideline and to evaluate using indirect outcome-based analytical performance specifications (APS). METHODS: MU was estimated using internal quality control data collected between October … Read more
Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0320. Online ahead of print. ABSTRACT OBJECTIVES: Therapeutic drug monitoring (TDM) of tacrolimus is essential due to its high inter- and intra-patient variability and narrow therapeutic window. Conventional venous blood sampling may limit sampling frequency and patient convenience. Capillary dried blood spot (DBS) sampling represents a patient-centric … Read more
Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0419. Online ahead of print. ABSTRACT OBJECTIVES: Traditionally, neonates were screened for classical galactosaemia in 4 of the 5 jurisdictions in Australia creating inequitable access to early intervention. A push to nationally harmonise newborn bloodspot screening enabled the state of Victoria to proceed with implementation of screening … Read more
Clin Chem Lab Med. 2026 May 13. doi: 10.1515/cclm-2026-0590. Online ahead of print. ABSTRACT Harmonization in laboratory medicine is increasingly recognized as a fundamental requirement to ensure interchangeable laboratory information, avoid confusion among users, and ultimately improve patient safety. However, current evidence continues to highlight substantial gaps in harmonization across several dimensions of the total … Read more
Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2025-1727. Online ahead of print. ABSTRACT OBJECTIVES: Pathological conditions may result in clinical chemical values exceeding the linearity range of laboratory methods. In clinical practice, not all tests require exact numerical values for patient management, as useful information can still be provided when results are reported to … Read more
Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0377. Online ahead of print. ABSTRACT A widely accepted approach to setting Analytical Performance Specifications (APS) in laboratory medicine is the Milan models. Milan model 1b is an approach where APS are developed based on patient classification, or clinical decision-making, noting that these factors link to the … Read more
Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0153. Online ahead of print. ABSTRACT OBJECTIVES: Few studies have systematically evaluated the factors contributing to laboratory errors in the analytical phase. This study analyzed five years of retest data to determine the frequency and characteristics of analytical errors across routine blood chemistry parameters, identify analytes most … Read more
Clin Chem Lab Med. 2026 May 5. doi: 10.1515/cclm-2026-0395. Online ahead of print. ABSTRACT OBJECTIVES: Plasma phosphorylated tau at threonine 217 (p-tau217) has emerged as a highly accurate blood-based biomarker of Alzheimer’s disease (AD) pathology. As disease-modifying anti-amyloid therapies enter clinical practice, scalable biomarkers with robust and clinically interpretable decision thresholds are required. However, evidence … Read more
Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2025-1137. Online ahead of print. ABSTRACT OBJECTIVES: This study developed a pseudoviral human rhinovirus (HRV) reference material using pseudovirus technology and integrating RT-dPCR with HPLC-IDMS to achieve accurate HRV RNA quantification, aiming to standardize HRV detection across labs and platforms. METHODS: We developed an RT-digital PCR (RT-dPCR) … Read more
Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2026-0580. Online ahead of print. ABSTRACT Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR) was introduced to enhance patient safety and ensure the availability of safe and effective diagnostics across the European Union. However, its implementation has led to substantial unintended consequences, including certification bottlenecks, … Read more
Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0289. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate the real-world impact of Point-of-Care Testing on care timeliness and patient flow in the emergency department. METHODS: A before-and-after, matched-cohort study was conducted involving 25,291 patients with Emergency Severity Index levels 3-4. A POCT group (n=8,746) was compared … Read more
Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0146. Online ahead of print. ABSTRACT OBJECTIVES: Dihydropyrimidine dehydrogenase (DPD) phenotyping through uracil and dihydrouracil determination is a well-established approach to identify (partial) DPD deficiencies prior to fluoropyrimidine chemotherapy. However, preanalytical stability has challenged this test for years. This study therefore investigated whether dried blood spots (DBS) … Read more
Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0577. Online ahead of print. ABSTRACT This article aims to define a minimum panel of essential laboratory tests to be used in emergency and disaster settings through expert consensus. A structured survey was distributed to the 24 members of the European Federation of Clinical Chemistry and Laboratory … Read more
Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1624. Online ahead of print. ABSTRACT OBJECTIVES: There has been a lot of interest in the field of laboratory medicine regarding the use of machine learning (ML)-based prediction models. The longitudinal ML-based Serum Tumor marker-based Outcome Prediction (STOP) model was previously developed to identify non-small cell lung … Read more
Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1356. Online ahead of print. ABSTRACT OBJECTIVES: Hypercalcemia has been associated with various non-specific minor neuropsychological symptoms but mainly in patient cohorts. Whether hypercalcemia is the cause or an innocent bystander in relation to these symptoms remains unclear. METHODS: We included 5,917 individuals from the Copenhagen City … Read more
Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0370. Online ahead of print. ABSTRACT OBJECTIVES: Plasma p-tau217 is a leading blood-based biomarker for Alzheimer’s disease (AD), offering high diagnostic accuracy and potential utility for treatment eligibility and monitoring. However, real-world data on concordance between cerebrospinal fluid (CSF) Aβ42/40 and plasma p-tau217 in routine clinical laboratory … Read more
Clin Chem Lab Med. 2026 Apr 20. doi: 10.1515/cclm-2026-0435. Online ahead of print. ABSTRACT OBJECTIVES: Large language models (LLMs) show promise for interpreting laboratory reports, yet real-world validation remains limited. This study evaluated five advanced LLMs in interpreting urinalysis reports for kidney diseases using real-world clinical data, providing empirical evidence for the utility of LLM-assisted … Read more
Clin Chem Lab Med. 2026 Apr 22. doi: 10.1515/cclm-2026-0080. Online ahead of print. ABSTRACT OBJECTIVES: To determine the prevalence of erythroid dysplasia and ring sideroblasts (RS) after peripheral blood stem cell transplantation (PBSCT), stratified by transplant type, and to assess the association with SF3B1 mutations and event-free survival (EFS). METHODS: In a retrospective single-center study, … Read more
Clin Chem Lab Med. 2026 Apr 21. doi: 10.1515/cclm-2026-0277. Online ahead of print. ABSTRACT INTRODUCTION: Brain-derived neurotrophic factor (BDNF) is a neurotrophin expressed in the central nervous system, where it supports synaptic plasticity, neuronal survival, and dendritic remodeling. Reduced circulating BDNF levels have been reported in several neurological and psychiatric disorders, increasing evidence links BDNF … Read more
Clin Chem Lab Med. 2026 Apr 20. doi: 10.1515/cclm-2025-1709. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate whether antinuclear antibody (ANA) titre or HEp-2 fluorescence patterns are associated with antiphospholipid antibody (aPL) serological intensity, and to examine component-specific complement abnormalities – particularly low C4 – as laboratory correlates compatible with classical-pathway involvement. METHODS: This retrospective … Read more
Clin Chem Lab Med. 2026 Apr 13. doi: 10.1515/cclm-2026-0079. Online ahead of print. ABSTRACT OBJECTIVES: The basophil activation test (BAT) is increasingly used for diagnosing IgE-mediated food allergies, yet its performance in cow’s milk allergy (CMA) remain insufficiently characterized in real-world pediatric practice. This study evaluates the diagnostic accuracy of BAT for CMA and identifies … Read more
Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2025-1673. Online ahead of print. ABSTRACT Adverse event in the perinatal period constitutes today the wider bulk of investigation. Perinatal asphyxia (PA) and prematurity are the common causes of injury of high risk pregnancies (HR) and can lead to perinatal death or cognitive and neuro-motor impairment in … Read more
Clin Chem Lab Med. 2026 Apr 16. doi: 10.1515/cclm-2025-1464. Online ahead of print. ABSTRACT OBJECTIVES: Low mitochondrial DNA copy number (mtCN) in leukocytes is a predictor of all-cause mortality, independent of age and sex. For malignant diseases, results about the prognostic value of leukocyte mtCN have been conflicting. Aim of the present study was to … Read more
Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2026-0262. Online ahead of print. ABSTRACT OBJECTIVES: To establish discrete and continuous age-specific reference intervals for serum alpha-fetoprotein in children and to evaluate whether continuous modeling improves interpretation during early infancy, when concentrations decline rapidly. METHODS: In this prospective, cross-sectional study, serum alpha-fetoprotein was measured in 3,680 … Read more
Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2026-0144. Online ahead of print. ABSTRACT OBJECTIVES: Testosterone is increasingly being measured in saliva due to the ease of collection, which puts a lower burden on patients and facilitates measurement in clinical and behavioral studies. Although the robustness of measuring testosterone in saliva using immunoassays has been … Read more
Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2026-0155. Online ahead of print. ABSTRACT OBJECTIVES: The CA 19-9 tumor marker measures the sialylated Lewis a blood group antigen (sLe(a)) expressed on circulating proteins. CA 19-9 is primarily used to monitor pancreatic and gastrointestinal cancers. Studies have demonstrated the lack of comparability of CA 19-9 assays. … Read more
Clin Chem Lab Med. 2026 Apr 13. doi: 10.1515/cclm-2026-0236. Online ahead of print. ABSTRACT OBJECTIVES: Multitarget stool tests are approved for colorectal cancer (CRC) screening. Here we developed a multitarget stool test based on the fecal immunochemical test (FIT) and two (NDRG4 and SDC2) DNA methylation markers with a simple calling algorithm. METHODS: FIT, quantitative … Read more
Clin Chem Lab Med. 2026 Apr 13. doi: 10.1515/cclm-2026-0093. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate the analytical performance and clinical workflow efficiency of the Flash10 molecular point-of-care testing (POCT) system for the detection of influenza A (FluA) and influenza B (FluB) viruses. METHODS: Throat swab specimens from 178 individuals presenting with influenza-like symptoms … Read more
Clin Chem Lab Med. 2026 Apr 13. doi: 10.1515/cclm-2026-0043. Online ahead of print. ABSTRACT OBJECTIVES: Several macro-hormones have been reported to date. Among them, macroprolactinemia is a common cause of hyperprolactinemia. Growth hormone (GH) and prolactin (PRL) are anterior pituitary hormones related by structure and function. The aim of this study was to clarify the … Read more
Clin Chem Lab Med. 2026 Apr 3. doi: 10.1515/cclm-2026-0109. Online ahead of print. ABSTRACT In precision medicine protein phenotypes are foreseen that combined with pattern recognition tools exhibit great potential in guaranteeing safe and accurate test results for patient management and intervention. For discovery purposes novel high-throughput technologies have emerged and this has led to … Read more
Clin Chem Lab Med. 2026 Apr 2. doi: 10.1515/cclm-2025-1694. Online ahead of print. ABSTRACT OBJECTIVES: This study aimed to compare the analytical and clinical performance of plasma glial fibrillary acidic protein (GFAP) across three immunoassay platforms. METHODS: Plasma GFAP was measured on three immunoassay platforms (Simoa HD-X, Maccura i1000, MS-Fast Pro 160) in 302 participants … Read more
Clin Chem Lab Med. 2026 Mar 20. doi: 10.1515/cclm-2026-0112. Online ahead of print. ABSTRACT OBJECTIVES: Indirect clinical outcome-based analytical performance specifications (APS) may offer a feasible alternative to direct studies but raise questions regarding data requirements and transferability. This study aimed to determine the minimum sample size for simulation-driven APS and to investigate the impact … Read more
Clin Chem Lab Med. 2026 Mar 20. doi: 10.1515/cclm-2026-0049. Online ahead of print. ABSTRACT OBJECTIVES: Patient-based real-time quality control (PBRTQC) represents a useful complement to traditional internal quality control methods, particularly in the continuous monitoring of routine analyses. Sodium, potassium, chloride, calcium, phosphorus, and magnesium are critical for patient safety. This study aimed to evaluate … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2026-0234. Online ahead of print. ABSTRACT Acute kidney injury (AKI) is a frequent complication in hospitalized patients, particularly those admitted to the intensive care unit (ICU), which leads to high rates of morbidity and mortality. Under these conditions, tissue inhibitor metalloproteinases-2 (TIMP-2) and insulin-like growth factor-binding protein … Read more
Clin Chem Lab Med. 2026 Mar 18. doi: 10.1515/cclm-2026-0075. Online ahead of print. ABSTRACT More than 30 years after German reunification, the units of measurement used for laboratory medical parameters still differ between eastern and western Germany. While the eastern German states predominantly use “SI” units, “conventional” units are common in medical facilities in the … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2025-1526. Online ahead of print. ABSTRACT OBJECTIVES: The inclusion of neurobiomarkers (NB) into routine clinical practice remains an unresolved challenge. Among the actions recommended by leading international institutions, a key priority is the establishment of reference curves during the perinatal period. The aim of the study was … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2026-0174. Online ahead of print. ABSTRACT Laboratory errors represent a critical yet underestimated threat to patient safety, with 26-30 % of reported errors adversely affecting patient care. Despite extensive scientific literature, no sustainable, open-access platform exists that allows laboratory professionals to rapidly access comprehensive information on error … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2026-0183. Online ahead of print. ABSTRACT OBJECTIVES: To estimate the frequency and characterize the distinctive features of the serum electrophoretic pattern associated with polyclonal elevations of IgG4, and to evaluate its clinical relevance. METHODS: A total of 127,827 serum protein electrophoresis (SPEP) analyses performed in our laboratory … Read more
Clin Chem Lab Med. 2026 Mar 17. doi: 10.1515/cclm-2026-0288. Online ahead of print. ABSTRACT OBJECTIVES: European legislation requires detailed performance evaluation of in vitro diagnostic medical devices (IVD-MD) by both commercial manufacturers (through the Conformité Européenne (CE) mark) and in-house (IH) IVDs. Little information is currently available on how CE- and IH-IVDs are mapped in … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2026-0168. Online ahead of print. ABSTRACT OBJECTIVES: Fluid biomarkers are central to the biological definition and diagnosis of Alzheimer’s disease (AD). Despite international recommendations, substantial variability persists in laboratory practices. This survey, promoted by the Committee: Harmonisation (C:H) of the European Federation of Clinical Chemistry and Laboratory … Read more
Clin Chem Lab Med. 2026 Mar 16. doi: 10.1515/cclm-2026-0032. Online ahead of print. ABSTRACT OBJECTIVES: Since apolipoprotein E4 (ApoE4) is associated with therapy-related adverse effects of anti-amyloid-β monoclonal antibodies in Alzheimer’s disease, such as amyloid-related imaging abnormalities, methods for determining the ApoE4 status are needed. The Lumipulse® ApoE4 and Pan-ApoE assays provide a practical approach, … Read more
Clin Chem Lab Med. 2026 Mar 13. doi: 10.1515/cclm-2026-0323. Online ahead of print. ABSTRACT The Joint Committee for Traceability in Laboratory Medicine (JCTLM) supports worldwide equivalence and comparability of measurement results in laboratory medicine to improve health care and facilitate national and international trade in in vitro diagnostic (IVD) medical devices. The 2025 biennial members … Read more
Clin Chem Lab Med. 2026 Mar 13. doi: 10.1515/cclm-2026-0309. Online ahead of print. ABSTRACT Point-of-care testing (POCT) represents a breakthrough technology in laboratory medicine that has expanded rapidly over the past three decades. Today, it accounts for approximately 25 % of all laboratory tests performed worldwide. POCT was initially implemented in critical care settings due … Read more
Clin Chem Lab Med. 2026 Mar 13. doi: 10.1515/cclm-2025-1743. Online ahead of print. ABSTRACT Neurofilament light chain (NfL) has been identified as a sensitive and broadly validated biomarker of neuroaxonal injury across multiple neurological conditions, including multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), and atypical parkinsonian syndromes. This position paper provides a … Read more
Clin Chem Lab Med. 2026 Mar 13. doi: 10.1515/cclm-2026-0057. Online ahead of print. ABSTRACT OBJECTIVES: Measurement of the concentrations of vitamin D metabolites is clinically important because abnormal levels are associated with perturbations in calcium and phosphorus homeostasis. The objective of this study was to evaluate analytical performance of the Ionify® Vitamin D iPack that … Read more
Clin Chem Lab Med. 2026 Mar 12. doi: 10.1515/cclm-2026-0251. Online ahead of print. ABSTRACT OBJECTIVES: Cervical lymph node metastases represent a key challenge in patients with differentiated thyroid carcinoma (DTC). Fine-needle aspiration cytology (FNAC) and thyroglobulin (Tg) measurement in fine-needle washout (FNA-Tg) are widely used but have recognized limitations. Cytokeratin 19 fragment 21-1 measurement in … Read more
Clin Chem Lab Med. 2026 Mar 12. doi: 10.1515/cclm-2026-0101. Online ahead of print. ABSTRACT Clinical endocrinology relies critically on high-quality biochemical data for diagnosis, therapeutic decisions, and long-term patient monitoring. As endocrine diagnostics grow more complex due to expanding test menus, technological advances, and changing patient populations, the need for a strong, structured partnership between … Read more
Clin Chem Lab Med. 2026 Mar 12. doi: 10.1515/cclm-2025-1169. Online ahead of print. ABSTRACT OBJECTIVES: Accurate measurement of 17α-hydroxyprogesterone (17-OHP) in human serum and plasma is required for steroid profiling, to ensure the appropriate diagnosis of congenital adrenal hyperplasia. Therefore, an isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) to quantify 17-OHP … Read more
Clin Chem Lab Med. 2026 Mar 5. doi: 10.1515/cclm-2025-1493. Online ahead of print. ABSTRACT OBJECTIVES: To determine the prevalence and clinical associations of rare HEp 2 indirect immunofluorescence ANA patterns and to evaluate their relationships with disease categories, ANA titers, and expression form. METHODS: We retrospectively analyzed 366,524 ANA tests performed between 2018 and 2024 … Read more
Clin Chem Lab Med. 2026 Mar 10. doi: 10.1515/cclm-2025-1366. Online ahead of print. ABSTRACT OBJECTIVES: The quantification of linezolid in serum and plasma matrices is crucial for therapeutic drug monitoring and pharmacokinetic studies. A reference measurement procedure (RMP) was developed and validated to provide accurate, precise, and reliable measurements, fit for its intended use while … Read more
Clin Chem Lab Med. 2026 Mar 5. doi: 10.1515/cclm-2026-0210. Online ahead of print. ABSTRACT A challenge in the implementation of rapid risk-stratification algorithms for patients with suspected acute coronary syndrome is the turnaround time for cardiac troponin (cTn) from blood sampling to reporting of results. Measurement of cTn in whole blood using point of care … Read more
Clin Chem Lab Med. 2026 Mar 3. doi: 10.1515/cclm-2026-0042. Online ahead of print. ABSTRACT Hemophilia A and B are X-linked hemorrhagic disorders, characterized by low/dysfunctional factor (F)VIII or FIX, respectively. The history of hemophilia treatment has evolved remarkably over time from the introduction of cryoprecipitate in the 1960s to plasma-derived factors in the 1970s. The … Read more
Clin Chem Lab Med. 2026 Mar 3. doi: 10.1515/cclm-2026-0083. Online ahead of print. ABSTRACT OBJECTIVES: We evaluated the diagnostic performance of the Atellica HEMA 580 hematology analyzer for complete blood count (CBC) parameters compared with the ADVIA 2120i and assessed its capability to flag abnormal cells, and determined optimal cut-offs for immature myeloid cell detection. … Read more
Clin Chem Lab Med. 2026 Mar 2. doi: 10.1515/cclm-2026-0088. Online ahead of print. ABSTRACT OBJECTIVES: Antiphospholipid antibodies (aPLs) are closely associated with recurrent spontaneous abortion (RSA) and adverse pregnancy outcomes (POs). Non-criteria aPLs may aid in diagnosing seronegative aPL-related RSA, but their limited performance often leads to missed or delayed diagnosis. This study aimed to … Read more
Clin Chem Lab Med. 2026 Mar 2. doi: 10.1515/cclm-2025-1679. Online ahead of print. ABSTRACT OBJECTIVES: Primary aldosteronism (PA) is a common cause of secondary hypertension. To address the specificity limits of immunoassays, we developed and validated an LC-MS/MS method for urinary aldosterone and tetrahydroaldosterone and established method-matched reference intervals for excretion in 24 h urine. … Read more
Clin Chem Lab Med. 2026 Feb 20. doi: 10.1515/cclm-2025-1376. Online ahead of print. ABSTRACT INTRODUCTION: Accurate assessment of T-cell clonality is key for diagnosing mature T-cell neoplasms. TRBC1-based flow cytometry provides a rapid, robust, and cost-efficient approach. This systematic review and meta-analysis assessed the diagnostic accuracy of TRBC1 flow cytometry (TRBC1-FC) for detecting T-cell clonality … Read more
Clin Chem Lab Med. 2026 Feb 5. doi: 10.1515/cclm-2025-1693. Online ahead of print. ABSTRACT OBJECTIVES: This stability study aimed to evaluate the stability of 48 biochemical analytes in pooled serum samples derived from leftover sera over 14 days at room temperature (RT) and at 2-10 °C, and to assess the consistency of storage effects across … Read more
