Effect of blood acidification on hemolysis-induced insulin degradationon December 11, 2025 at 1:09 pm December 11, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Şerif Ercan
Integrating CRISPR with SERS: Toward intelligent point-of-care diagnostics of the futureon December 11, 2025 at 1:09 pm December 11, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Biqing Chen, Jiayin Gao, Haizhu Sun, Yinghan Zhao, Yan Liu, Xiaohong Qiu, Yang Li
Extreme hypokalemia in an asymptomatic 40-year-old cachectic maleon December 11, 2025 at 12:07 pm December 11, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Stanislas Francois, Sreekanth Rajagopal, Anne Boutten, Alexandre Raynor, Katell Peoc’h
Mass spectrometry reveals limitations of serum immunofixation electrophoresis in monitoring lambda light chain myelomaYu Chenon December 10, 2025 at 11:00 am December 10, 2025 Clin Chem Lab Med. 2025 Dec 11. doi: 10.1515/cclm-2025-1337. Online ahead of print. NO ABSTRACT PMID:41369217 | DOI:10.1515/cclm-2025-1337
Shift happens: the utility of external quality assessment data in evaluating folate lot changesRachel Marringtonon December 10, 2025 at 11:00 am December 10, 2025 Clin Chem Lab Med. 2025 Dec 11. doi: 10.1515/cclm-2025-1569. Online ahead of print. NO ABSTRACT PMID:41369135 | DOI:10.1515/cclm-2025-1569
Comparability of venous and capillary blood measurements for a host-protein test differentiating bacterial from viral infectionson December 10, 2025 at 10:45 am December 10, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Mary Hainrichson, Nitzan Shamir, Naftalie Senderovich, May Levin, Husein Darawsha, Ayelet Raz, Salim Halabi, Oded Shaham, Roy Navon, Tanya M. …
Read more Rapid identification and quantification of residual daratumumab in multiple myeloma patients by MALDI – TOF mass spectrometryon December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Hou-Long Luo, Huan Ding, Fan Chen, Yuxi Wang, Lin Zhou, Peng Ye, Hui Yu, Shangying Wu, Weijie Xie, …
Read more HOX genes and tumor metastasis: epigenetic regulatory mechanismson December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Junwei Li, Jinhua Yan, Shubing Zhang
Galectin-3 as a cardiac biomarkeron December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Asif Ahmad Bhat, Yahia Alghazwani, Kumarappan Chidambaram, M.M. Rekha, Samir Sahoo, Pavan Goud, Nadeem Sayyed, Vikas Jakhmola, Moyad …
Read more Evaluation of three NT-proBNP assays for heart failureon December 10, 2025 at 10:45 am December 10, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Isaiah K. Mensah, Brittany Roemmich, Sydny Lawless, Alexis Wysocki, David Daghfal, Christian J. Hunter, Christopher W. Farnsworth
Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementationJacopo Gervasonion December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1336. Online ahead of print. ABSTRACT OBJECTIVES: The aim of this study was to evaluate the impact of introducing an autonomous courier …
Read more A specific-neonatal hemolysis correction model for accurate potassium assessment in blood samples with in vitro hemolysisJinmei Lion December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1484. Online ahead of print. ABSTRACT OBJECTIVES: Accurate determination of blood potassium levels in neonates presents significant clinical challenges, primarily attributable to …
Read more The European Health Data Space: challenges and opportunities for laboratory medicinePieter Vermeerschon December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1618. Online ahead of print. NO ABSTRACT PMID:41364080 | DOI:10.1515/cclm-2025-1618
Commutability assessment of NIST SRM 3666 albumin and creatinine in frozen human urine among routine clinical laboratory measurement procedureson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Ashley Beasley-Green, Johanna E. Camara, Elena S.C. Wood, N. Alan Heckert, W. Greg Miller, Lorin M. Bachmann, Laura …
Read more FTIR spectroscopy of plasma exosomes reveals distinct lipidomic and proteomic signatures for early Alzheimer’s disease detectionon December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Rishabh Singh, Abhay Mishra, Vipin Kumar, Anu Gupta, Sadaqa Zehra, Neerja Rani, Renu Dhingra, Gyan Prakash Modi, Krishna …
Read more qPCR-melting curve analysis in molecular diagnosticson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Li He, Nanqiu Peng, Zihan Ran, Xiaoshan Rong, Zhenghu Chen
Aptasensors in colorectal Cancer: Emerging tools for precision diagnosticson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Qamar Abuhassan, Ali M. Atoom, R. Roopashree, Jaya Bhanu Kanwar, T. Sudhakar, Vipasha Sharma, Ashish Singh Chauhan, Oybek …
Read more Ovarian cancer biosensors: established glycoproteins to emerging molecular biomarkerson December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yalda Jahanbani, Farzaneh Fathi, Hosein azizi, Parvin Bastani, Faride Ranjbari
Multi-omic biomarker detection in ovarian canceron December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Qamar Abuhassan, Ghada Al-Assi, M.M. Rekha, Kabita Chanania, M. Bavanilatha, Vimal Arora, Aashna Sinha, Mehrigul Hayitova
Urinary exosomes: Emerging biomarkers for urinary tract infectionon December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Narbaev Zafar, Umurzoqov Dilmurod, Islom Kadirov, Eshchanova Gulbakhor, Sidikov Akmal, Gulomova Gulnora, Sharipov Rustam, Tadjibaeva Muyassar Karimbaevna, Ravshan …
Read more Response to: Shift happens: The utility of external quality assessment data in evaluating folate lot changes. https://doi.org/10.1515/cclm-2025-1569Anders Larssonon December 6, 2025 at 11:00 am December 6, 2025 Clin Chem Lab Med. 2025 Dec 8. doi: 10.1515/cclm-2025-1575. Online ahead of print. NO ABSTRACT PMID:41351029 | DOI:10.1515/cclm-2025-1575
Matrix commutability for ApoA1, ApoB, and lipoprotein(a) testing: Comparison between serum and heparinized plasmaon December 6, 2025 at 9:23 am December 6, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Meryem Benamour, Hadrien Cools, Yasmine Boufelliga, Catherine Fillée, Damien Gruson
Evaluation of a novel host protein-based assay for ruling out bacterial infections in patients with suspected respiratory tract infections at an urban academic hospitalon December 6, 2025 at 9:23 am December 6, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yaxin Li, David Bodnar, Hnin Ingyin, Samantha Maniccia, Zhen Zhao, He S. Yang
Evaluation of iMS-IP assay for the detection and typing of monoclonal immunoglobulinson December 5, 2025 at 2:18 pm December 5, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yu Chen, Liangshun You, Li Zhu, Xuejiao Yin, Qiumei Yao, Shengnan Ding, Jiaying Ge, Yi Liu, Hongyan Tong, …
Read more Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):629-631. doi: 10.1093/clinchem/hvae218. NO ABSTRACT PMID:41342347 | DOI:10.1093/clinchem/hvae218
Breaking Barriers in Biosensing: Real-Time Continuous Protein Detection in Interstitial Fluid December 4, 2025 Clin Chem. 2025 Jun 3;71(6):723-724. doi: 10.1093/clinchem/hvaf033. NO ABSTRACT PMID:41342350 | DOI:10.1093/clinchem/hvaf033
Commentary on Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):632-633. doi: 10.1093/clinchem/hvaf008. NO ABSTRACT PMID:41342349 | DOI:10.1093/clinchem/hvaf008
Commentary on Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):631-632. doi: 10.1093/clinchem/hvaf007. NO ABSTRACT PMID:41342348 | DOI:10.1093/clinchem/hvaf007
Fragmentation patterns of pathogen-derived cell-free DNA as a promising non-invasive biomarker for bloodstream infection diagnosison December 4, 2025 at 11:53 am December 4, 2025 Publication date: December 2025 Source: Practical Laboratory Medicine, Volume 47 Author(s): Qichuan Fu, Jie Wang, Liya Yue, Tianyu Lu, Wenyu Shi, Cuidan Li, Xiaoyuan Jiang, Peihan Wang, Fei Chen
Liquid chromatography-mass spectrometry quantitation and prevalence of medetomidine and xylazine in New Haven, Connecticuton December 4, 2025 at 11:53 am December 4, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Jillian Kodger, Gina Cassella-McLane, Mallorie Iozzo, Joe M. El-Khoury
One‑carbon pathway gene expression analyses in blood samples of subjects with trisomy 21on December 4, 2025 at 11:53 am December 4, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Beatrice Vione, Alessandro Maria Gaudesi, Francesca Antonaros, Michela Cicilloni, Lorenza Vitale, Allison Piovesan, Maria Chiara Pelleri, Pierluigi Strippoli, …
Read more PREEMPT’ing Overreliance on Peripheral Blood-Based ColoRectal Cancer Screening December 4, 2025 Clin Chem. 2025 Dec 3:hvaf137. doi: 10.1093/clinchem/hvaf137. Online ahead of print. NO ABSTRACT PMID:41335517 | DOI:10.1093/clinchem/hvaf137
Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing December 4, 2025 Clin Chem. 2025 Dec 3:hvaf155. doi: 10.1093/clinchem/hvaf155. Online ahead of print. ABSTRACT BACKGROUND: Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) encompasses the use of antiviral medications to prevent HIV acquisition …
Read more Phosphorylated Tau in Developing and Degenerating Brains: A 30-Year-Old Puzzle Revisited December 4, 2025 Clin Chem. 2025 Dec 3:hvaf161. doi: 10.1093/clinchem/hvaf161. Online ahead of print. NO ABSTRACT PMID:41335514 | DOI:10.1093/clinchem/hvaf161
Diagnostic accuracy of non-coding RNA for detecting endometriosis: A systematic review and meta-analysison December 3, 2025 at 9:31 am December 3, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Seyed Danial Mohammadi, Abasali Keshtkar, Ashraf Moini, Tayebeh Rastegar, Faezeh Heydarikhah, Anahid Shafie, Mohammadreza Ghasemi, Hojat Ghasemnejad Berenji …
Read more Clinical laboratory testing of blood from patients presenting to the emergency department with acute bleeding due to factor Xa inhibitors: An unmet medical needon December 3, 2025 at 9:31 am December 3, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Alan H.B. Wu, W. Franklin Peacock
Clinical assessment and acceptance criteria for continuous glucose monitoring (CGM) system performance: A proposed guideline by the IFCC Working Group on CGMon December 3, 2025 at 9:31 am December 3, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Stefan Pleus, Manuel Eichenlaub, Pradeep Kumar Dabla, Peter Diem, Elisabet Eriksson Boija, Marion Fokkert, Rolf Hinzmann, Johan Jendle, …
Read more Aberrant Plasma Cells in the Absence of M-Protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1195-1199. doi: 10.1093/clinchem/hvaf097. NO ABSTRACT PMID:41329021 | DOI:10.1093/clinchem/hvaf097
Commentary on Aberrant Plasma Cells in the Absence of M-protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1200. doi: 10.1093/clinchem/hvaf117. NO ABSTRACT PMID:41329020 | DOI:10.1093/clinchem/hvaf117
Commentary on Aberrant Plasma Cells in the Absence of M-Protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1201. doi: 10.1093/clinchem/hvaf130. NO ABSTRACT PMID:41329019 | DOI:10.1093/clinchem/hvaf130
Transdermal GFR Signals a New Horizon in Renal Diagnostics December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1281-1282. doi: 10.1093/clinchem/hvaf106. NO ABSTRACT PMID:41329018 | DOI:10.1093/clinchem/hvaf106
Extended verification of an automated MALDI-TOF mass spectrometry system for high throughput serum M-protein measurementLouis Nevejanon December 2, 2025 at 11:00 am December 2, 2025 Clin Chem Lab Med. 2025 Dec 3. doi: 10.1515/cclm-2025-0894. Online ahead of print. ABSTRACT OBJECTIVES: This study aimed to perform an extended analytical verification of the Immunoglobulin Isotypes (GAM) for …
Read more Impact of Clinical Variables on cfDNA Fragmentomic Signatures and Their Potential as Confounders in Cancer Detection December 2, 2025 Clin Chem. 2025 Dec 2:hvaf163. doi: 10.1093/clinchem/hvaf163. Online ahead of print. ABSTRACT BACKGROUND: Circulating cell-free DNA (cfDNA) fragmentomic features, such as fragment size and end motifs, have emerged as promising …
Read more Volatile organic compound signatures in breast cancer: A pilot study on cell-based detectionon December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Ana J. Tenorio-Salazar, Fernanda M. Orduña-Medina, Boris Mizaikoff, Jan Mitrovics, Lorena Díaz de León-Martínez, Luz E. Alcántara-Quintana
Identification of lncRNA ZNF252P-AS1 as a novel diagnostic and prognostic biomarker for breast cancer patients: An integrated bioinformatics and experimental analysison December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Nahla E. El-Ashmawy, Mariam A. Abo-Saif, Sara M. Hamouda, Eman G. Khedr
Unveiling regional patterns of IgE sensitization to peanut, hazelnut, and walnut in Italy: a nationwide bottom-up molecular surveyon December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Giulia Marcassa, Danilo Villalta, Valeria Villella, Simonetta Friso, Maria Barrale, Ignazio Brusca, Enrico Scala
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of progesterone in human serum and plasmaSara Cheikh Ibrahimon December 1, 2025 at 11:00 am December 1, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-0514. Online ahead of print. ABSTRACT OBJECTIVES: Progesterone regulates reproductive processes and is used clinically to monitor ovarian function in people experiencing …
Read more Reducing inappropriate vitamin D testing: an analysis of three sequential diagnostic stewardship interventions and the carbon footprint implicationson November 29, 2025 at 3:43 pm November 29, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): C. Hughes, M.A. Myers, M. Tickell-Painter, M. Aitchison, L. Roberts, R.J. Shorten
Serum placental growth factor: Pre-analytical stability, comparison of blood derivates and interference from biotin and hemolysison November 29, 2025 at 12:40 pm November 29, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Mette Tiedemann Skipper, Tina Parkner, Henriette Ladegård Skov, Cindy Soendersoe Knudsen
Evaluation of the commutability of lombardy region EQA control materials for enzymes, calcium, and creatinineon November 29, 2025 at 12:40 pm November 29, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Anna Carobene, Matteo Vidali, Ferruccio Ceriotti, Antonella Alberghini, Adele Arcangeli, Walter Bellandi, Paola Cappelletti, Lorenzo Cerutti, Alice Cotellessa, …
Read more An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasmaSara Cheikh Ibrahimon November 29, 2025 at 11:00 am November 29, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-0179. Online ahead of print. ABSTRACT OBJECTIVES: Dehydroepiandrosterone sulfate (DHEAS), the sulfate ester of dehydroepiandrosterone, is one of the most common steroid …
Read more The hook effect of an immunoassay results in a series of pediatric patients with elevated total immunoglobulin E: implications for dilution protocols and method comparisonOleg Melnichukon November 29, 2025 at 11:00 am November 29, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-1492. Online ahead of print. NO ABSTRACT PMID:41316679 | DOI:10.1515/cclm-2025-1492
Altered PCSK9 plasma levels after preeclampsia in the PERLA-Brazil studyon November 28, 2025 at 5:41 pm November 28, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Isabella Macedo Costa, Thaíse Emilia Moreira da Silva, Letícia Gonçalves Silva, Ana Paula Silva Ferreira, Thays Santos da …
Read more From conventional to personalized reference intervals and decision limits: addressing latent errors in the post-post analytical phaseAbdurrahman Coskunon November 27, 2025 at 11:00 am November 27, 2025 Clin Chem Lab Med. 2025 Nov 28. doi: 10.1515/cclm-2025-1338. Online ahead of print. ABSTRACT Laboratory errors are an important component of medical errors and are predominantly associated with the extra-analytical …
Read more Immunofixation electrophoresis image interpretation using transfer learning methodon November 27, 2025 at 1:50 pm November 27, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Berrin Oztas, Irfan Kosesoy
Attention-based deep learning for immunoglobulin typing from electrophoresis and laboratory dataon November 27, 2025 at 1:50 pm November 27, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Long Zhao, Ruihua Liu, Tian Zhang, Weiqing Song, Ning Song
Annual meeting of the Royal Belgian Society of Laboratory Medicine (RBSLM): “Beyond the Surface – Clinical biology of the apparently healthy individual”on November 27, 2025 at 11:00 am November 27, 2025 Clin Chem Lab Med. 2025 Nov 27. doi: 10.1515/cclm-2025-1532. Online ahead of print. NO ABSTRACT PMID:41305926 | DOI:10.1515/cclm-2025-1532
Addressing the silent epidemic of recreational nitrous oxide use: a position, call to action and recommendations by the European Federation of Clinical Chemistry and Laboratory Medicine Committee on Biological Markers of Nitrous Oxide AbuseGuillaume Grzychon November 26, 2025 at 11:00 am November 26, 2025 Clin Chem Lab Med. 2025 Nov 20. doi: 10.1515/cclm-2025-1060. Online ahead of print. ABSTRACT Recreational nitrous oxide (N2O) use has emerged as a growing public health concern, with increasing reports …
Read more Combining the calibrator uncertainty and the long-term measurement uncertainty? A comment to the ISO/TS 20914 guidelineArne Åsbergon November 25, 2025 at 11:00 am November 25, 2025 Clin Chem Lab Med. 2025 Nov 26. doi: 10.1515/cclm-2025-1389. Online ahead of print. NO ABSTRACT PMID:41289554 | DOI:10.1515/cclm-2025-1389
Performance evaluation of a new high-sensitivity cardiac troponin T assay: hs-cTnT (CLIA) assayXin Shuon November 25, 2025 at 11:00 am November 25, 2025 Clin Chem Lab Med. 2025 Nov 26. doi: 10.1515/cclm-2025-1258. Online ahead of print. ABSTRACT OBJECTIVES: The Fourth Universal Definition of Myocardial Infarction recommends high-sensitivity cardiac troponin (hs-cTn) as the preferred …
Read more Analytical Imprecision and Therapeutic Intervals for Lithium – Are There Implications for Old Age Patients with Bipolar Disorder?on November 25, 2025 at 4:00 pm November 25, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Janet Zhou, Demitra Tsoukalas, Nethra Chittiprol, Peter Kavsak, Felix Leung, Jennifer Taher, Zahraa Ali-Mohammed, Saranya Arnoldo, Heather Tysick, Lei Fu, …
Read more Cyclical fluctuations of iron biomarkers in women: Diagnostic implications for iron deficiencyon November 23, 2025 at 2:41 pm November 23, 2025 Publication date: December 2025 Source: Practical Laboratory Medicine, Volume 47 Author(s): Sixtus Aguree, Arthur Owora, Patricia Silveyra
Lipidomic machine learning predictor for progression of gastric canceron November 23, 2025 at 2:41 pm November 23, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Xian Ding, Jun Zhou, Zhaoying Wang, Yunhai Bo, Zeper Abliz, Zhuoling An, Fen Yang, Yanhua Chen
Genotypic and phenotypic characterization of critical pediatric cardiomyopathy: A 20-patient cohort studyon November 23, 2025 at 2:41 pm November 23, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Yuanyuan Xu, Min Li, Xiaoling Zhao, Yaping Liang, Yanyan Chai, Chao Dai, Wenjia Tong, Danqun Jin
Implementation of an automated alert system of critical results in hospitalized and emergency patientsAngela García-de la Torreon November 21, 2025 at 11:00 am November 21, 2025 Clin Chem Lab Med. 2025 Nov 24. doi: 10.1515/cclm-2025-1312. Online ahead of print. ABSTRACT OBJECTIVES: The accurate and timely identification and notification of critical results (CR) are crucial to ensure …
Read more A case of late-onset carbamoyl phosphate synthetase 1 deficiency: diagnostic challenges and management in a low-resource settingon November 21, 2025 at 4:56 pm November 21, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Xiaopu Cui, Sixian Guo, Yu Zhang, Huixin Zhang, Hongxin Tian, Huafang Yang, Huacheng Zheng, Baoguang Li
Association of hypertension and genetic variants in MYH9 and BMPR1B with increased proteinuria in sickle cell diseaseon November 21, 2025 at 4:56 pm November 21, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): El Hadji Malick Ndour, Kuthala Mnika, El Hadj Ousmane Sene, Fatou Gueye Tall, Victoria Nembaware, Indou Deme Ly, Moussa Seck, …
Read more Effective detection of bias and variability using R-value statistics in the even-check method for real-time quality controlon November 21, 2025 at 9:26 am November 21, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Noriko Hatanaka, Yoshikazu Yamamoto, Eiji Kuramura, Naoharu Nagai, Masashi Shimada, Mikio Kamioka
Establishing age-specific reference intervals for serum beta-human chorionic gonadotropin using Hoffmann and nonparametric methods: A big data study based on laboratory databaseson November 20, 2025 at 1:45 pm November 20, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Xu Zhu
Targeted LC-MS/MS metabolomics reveals distinctive tryptophan pathway signatures in pneumocystis jirovecii pneumoniaon November 20, 2025 at 1:45 pm November 20, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Feng Chen, Xiaoxia Yang, Yayun Tan, Huanhuan Li, Yan Yan, Xiang Zhao, Chengfeng Qiu
Screening the nutritional risk in critically ill patients: development and validation of a new nutritional-inflammatory prognostic score (NIPS) to predict short-term mortalitySalam Bennouar Abdelghani Bachir-Cherif Fella-Amina Marfoua Ihcen Khacheba Adel Boudahdir Nabil Raaf Samia Abdi a Faculty of Medicine, University Blida 1, Blida, Algeriab Faculty of Medicine, University of Algiers 1, Algiers, Algeriaon November 7, 2025 at 4:01 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 555-570.
Selection of stable reference genes for qPCR-based analysis of circulating cell-free DNA levels in peripheral blood of neuroblastoma patientsYan Lei Zhen Yang Yuantao Zhou Li Li a Kunming Medical University, Kunming, Yunnan, Chinab Kunming Children’s Hospital, Children’s Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, Chinaon November 4, 2025 at 11:24 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 590-598.
Resolving falsely elevated vancomycin levels in KIMS immunoassay due to monoclonal IgM interferenceGo Eun Bae Sang-Mi Kim Hae-il Park Soo-Youn Lee Hyung-Doo Park a Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Koreab Department of Laboratory Medicine and Genetics, Chosun University Hospital, Chosun University School of Medicine, Gwangju, Republic of Koreac Deprartment of Laboratory Medicine and Genetics, The Catholic University of Korea, Bucheon St. Mary’s Hospital, Bucheon, Koread Department of Medical Device Management and Research, SAIHST, Sungkyunkwan University, Seoul, Koreaon November 3, 2025 at 1:23 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 549-554.
The association between serum MST1 and the prognosis in patients with chronic rhinosinusitis with nasal polyps after functional endoscopic sinus surgeryMing Yang Haohua Zhu Qian Liu E.N.T. Department, The First Hospital of Nanchang City, Nanchang, Jiangxi Province, P.R. Chinaon October 1, 2025 at 1:15 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 519-525.
Gestational age-specific reference intervals for placental growth factor and its application in singleton and twin pregnancies: a population-based cohort studyKaiqi Wu Shaomin Zhou Yongying Bai Binbin Yin Baohua Li Bo Zhu Shuai Li a Department of Clinical Laboratory, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Chinab Department of Obstetrics and Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Chinaon October 9, 2025 at 10:24 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 526-537.
Paediatric, age-specific reference intervals for reticulocyte count on Abbotts Alinity hq platformRie H. Nygaard Rie McGrail Cristine Betzer Department of Clinical Biochemistry, Gødstrup Hospital, Herning, Denmarkon October 6, 2025 at 5:53 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 538-542.
Stability of complete blood count parameters in low volume tubes under different storage conditionsAyşen Caniklioğlu Emiş Deniz Akbulut a Department of Medical Biochemistry, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkeyb Department of Medical Biochemistry, Ankara Bilkent City Hospital, Ankara, Turkeyon October 9, 2025 at 2:12 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 543-548.
Comparative evaluation of diagnostic and analytical performance of DIRUI FUS-200 and MUS-3600 fully automated urine analyzersBerrin Oztas Fatih Hunc Berna Yildirim Şik Hale Kir Department of Biochemistry, School of Medicine, Kocaeli University, İzmit, Turkeyon November 7, 2025 at 8:43 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 571-580.
Circulating microRNA-222 and microRNA-146b: a potential differentiating tool between benign and malignant thyroid nodulesRamy Samir Assaad Wafaa Saad Ragab Rania El Tayfi Amel Gaber El Sheredy a Chemical Pathology Department, Medical Research Institute – Alexandria University, Alexandria, Egyptb Clinical Pathology Department, Damanhour Oncology Center, Damanhour, Egyptc Microbiology Department, Medical Research Institute – Alexandria University, Alexandria, Egypton November 6, 2025 at 12:39 pm November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 581-589.
Mitigating electrolyte measurement discrepancies in high triglycerides samples: a comparative analysis of direct and indirect ISE for sodium, potassium and chloride measurementsYulan Hou Junqun Liao Zhixue Wang Changli Xie a Department of Laboratory Medicine, Bishan Hospital of Chongqing Medical University, Bishan Hospital of Chongqing, Chongqing, Chinab Department of Laboratory Medicine, First Affiliated Hospital of Chongqing Medical University, Chongqing, Chinaon November 11, 2025 at 1:12 am November 20, 2025 Volume 85, Issue 7, NOVEMBER 2025, Page 599-607.
The Changing Face of Academic Laboratory Medicine-A Decade Later and Beyond November 19, 2025 Clin Chem. 2025 Nov 19:hvaf132. doi: 10.1093/clinchem/hvaf132. Online ahead of print. NO ABSTRACT PMID:41259117 | DOI:10.1093/clinchem/hvaf132
Recommendations from the IFCC Working Group on Laboratory Errors and Patient Safety for the Global Adoption of an Essential Quality Indicators Panel in Laboratory MedicineVincent De Guireon November 19, 2025 at 11:00 am November 19, 2025 Clin Chem Lab Med. 2025 Nov 20. doi: 10.1515/cclm-2025-1462. Online ahead of print. ABSTRACT OBJECTIVES: To maximize participation in the international standardization effort, this recommendation aims to update the international …
Read more The impact of pathological fluctuations versus biological variation on the interpretation of laboratory valueson November 18, 2025 at 3:47 pm November 18, 2025 Publication date: December 2025 Source: Practical Laboratory Medicine, Volume 47 Author(s): Ariel Mundo Ortiz, Jean-Philippe Emond, Vincent Weng-Jy Cheung, Sahar Saeed, Philippe Desmarais, François Larivière, Pierre-Olivier Hétu, Robert Goulden, Quoc …
Read more Nanobiosensors for Key Inflammatory Mediators: Cytokines, Histamine, and Prostaglandinson November 18, 2025 at 1:57 pm November 18, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Reza Soleimany, Elham Shaterian, Hamed Shaterian, Ahmad Mobed
Pre-Analytical Considerations in the simultaneous quantification of Ketone Bodies, Lactate, pyruvate and TCA cycle intermediateson November 18, 2025 at 11:49 am November 18, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Kaitlyn Berchier, Chiara Nyffeler, Stephen Bruce, Clothilde Roux, Jean-Marc Nuoffer, Matthias Gautschi, Alexander Laemmle, Déborah Mathis
Cystatin C in atherosclerotic cardiovascular diseaseon November 17, 2025 at 12:15 pm November 17, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Siarhei A. Dabravolski, Natalia V. Elizova, Elizaveta R. Korchagina, Olga N. Maltseva, Vsevolod V. Pavshintsev, Alexander N. Orekhov …
Read more Sample tracking in whole exome sequencingon November 16, 2025 at 10:52 am November 16, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Xunhong Yang, Zhilong Li, Benyang Xiao, Weiyu Zhai, Yu Tan, Li Wang
Uracil in plasma: comparison of two in-house-developed LC-MS/MS methodsSvend H Hansenon November 15, 2025 at 11:00 am November 15, 2025 Clin Chem Lab Med. 2025 Nov 17. doi: 10.1515/cclm-2025-0782. Online ahead of print. ABSTRACT OBJECTIVES: To prevent intoxication with 5-fluorouracil (5-FU) during chemotherapy, the initial measurement of plasma uracil levels …
Read more A study of the performance of different methods for measuring serum lithiumXiaoyu Fanon November 15, 2025 at 11:00 am November 15, 2025 Clin Chem Lab Med. 2025 Nov 17. doi: 10.1515/cclm-2025-1432. Online ahead of print. NO ABSTRACT PMID:41240329 | DOI:10.1515/cclm-2025-1432
Concurrent diagnosis of spinal muscular atrophy and trisomy 21: Value of comprehensive analysis in prenatal genetic testingon November 15, 2025 at 2:20 pm November 15, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Roshan Shaikh, Prasanna Sethu, Jagan Shanmugam, Phani Nagaraja M., Prakash Gambhir, Mukul Chotrani
Glycosylation-associated plasma SNORD99 as a novel diagnostic biomarker for early-stage lung adenocarcinomaon November 15, 2025 at 2:20 pm November 15, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Lulu Yang, Jiali Liu, Boyang Wang, Yufei Sheng, Zhiqi Hong, Lei Zheng, Zhuobin Deng, Chengwei Zhou, Wentao Hu, …
Read more Incorrectly prepared formula contributing to severe hypovolemic hypernatremia in enteral tube-fed children: A report of two caseson November 15, 2025 at 2:20 pm November 15, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Lawrence de Koning, Shelina M. Jamal, Catherine Ross, Michael J. Esser, Erin Pols
Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Departmenton November 15, 2025 at 2:20 pm November 15, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Bertil Lindahl, Alexander JF Thurston, Yong Yong Tew, Michael McDermott, Takeshi Fujisawa, Stephen Lynch, Jamie G Cooper, Alasdair J Gray, …
Read more A tale of two variants: The first reported case of hemoglobin Rush and hemoglobin S in a compound heterozygoteon November 14, 2025 at 1:46 pm November 14, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Gabriela Alves Bernardino, Júlia Junqueira Ruiz …
Read more SeraSeq reference materials support non-invasive cfDNA screening methodson November 14, 2025 at 1:46 pm November 14, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Sylvie Giroux, Seyedeh Saideh Daryabari, André Caron, François Rousseau
The hemopexin-apolipoprotein B product: a novel biomarker integrating oxidative stress and lipid metabolism for coronary artery disease risk stratificationon November 14, 2025 at 1:46 pm November 14, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Yinsheng Jin, Kun Chen, Qunxiong Fan
A large-scale survey on the knowledge, attitude, and practice of patient-based real-time quality control in Chinaon November 14, 2025 at 1:46 pm November 14, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Dong Leng, Mengxue Lyu, Li Wei, Xueling Shang, Xia Lou, Minglong Zhang, Yali Zhou, Tony Badrick, Rui Zhou, On behalf …
Read more Rapid detection of Helicobacter pylori and its virulence genes by fluorescence-chromogenic double-indicator LAMP (FC-LAMP)on November 14, 2025 at 1:46 pm November 14, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Yanghe Liu, Sijie Yin, Shiyue Chen, Chunlei Zhang, Nasifu Lubanga, Ping Tai, Mengqiu Xiong, Boyue Fan, Xincheng Yang, …
Read more Olink proteomics profiling platform reveals myocardial metabolism-associated protein biomarkers in heart failure with preserved ejection fraction (HFpEF)on November 14, 2025 at 1:46 pm November 14, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Xinyun Chen, Yimei Huang, Liping Liu, Yuchi Hu, Songyuan Dai, Hongning Li, Chuanxin Li, Siqi Nian, Xi Zhai, …
Read more Gestational age-specific changes and reference intervals of coagulation parameters and early biomarkers of thrombosis in Chinese pregnant womenon November 14, 2025 at 1:46 pm November 14, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Ruochen Zhang, Wei Shen, Yi Gu, Junxiang Mao, Wenyan Shen, Min Li, Aimin Zhao, Jingyi Zhou
