Analytical Performance Comparison of Three Quantitative Hepatitis B Surface Antigen Assays

Clin Chem. 2026 Jan 16:hvaf191. doi: 10.1093/clinchem/hvaf191. Online ahead of print. ABSTRACT BACKGROUND: Quantitative hepatitis B surface antigen (qHBsAg) assays are important tools for monitoring hepatitis B virus (HBV) infection and treatment response and constitute the primary endpoint in most HBV antiviral trials. To date, no qHBsAg assay has been authorized by the FDA for … Read more

Assessment for potential bias in multiplexed IL-10 and TNF-α from plex countWade M Sanderson January 16, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 19. doi: 10.1515/cclm-2025-0458. Online ahead of print. ABSTRACT OBJECTIVES: Multiplex arrays offer a high-throughput, cost-effective means for quantifying multiple analytes simultaneously, essential for large-scale biomarker research. However, the shared reactive environment in multiplex assays could lead to variations in results compared to single plex assays, potentially impacting outcomes. This … Read more

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