Clinical Chemistry

Association of Serum Uromodulin and Carbamylated Albumin with All-Cause and Cardiovascular Mortality in Patients with No or Mild Chronic Kidney Disease

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Clin Chem. 2025 Dec 16:hvaf166. doi: 10.1093/clinchem/hvaf166. Online ahead of print. ABSTRACT BACKGROUND: Serum uromodulin (SUmod) and carbamylated albumin (C-Alb) are emerging biomarkers for chronic kidney disease (CKD) progression and mortality. SUmod reflects tubular health, while C-Alb is associated with excretory kidney function, CKD progression, and cardiovascular (CV) mortality. We hypothesized that the combined use … Read more

Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing

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Clin Chem. 2025 Dec 3:hvaf155. doi: 10.1093/clinchem/hvaf155. Online ahead of print. ABSTRACT BACKGROUND: Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) encompasses the use of antiviral medications to prevent HIV acquisition in individuals without HIV who are at risk. Currently available HIV PrEP medications are nucleoside reverse transcriptase inhibitors and integrase inhibitors. HIV testing is required … Read more

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