Cardiac Biomarkers in Pulmonary Embolism: Revealing or Redundant?
Clin Chem. 2025 Apr 16:hvaf019. doi: 10.1093/clinchem/hvaf019. Online ahead of print. NO ABSTRACT PMID:40238127 | DOI:10.1093/clinchem/hvaf019
Clinical Chemistry
Instrument Multiplexing: Amplified Throughput for Measurement of Vitamin B1 in Whole Blood Using Parallel Liquid Chromatography Systems Interfaced to a Single Mass Spectrometer
Clin Chem. 2025 Apr 9:hvaf029. doi: 10.1093/clinchem/hvaf029. Online ahead of print. ABSTRACT BACKGROUND: Thiamine diphosphate (TDP), the active form of vitamin B1, plays an essential role in energy metabolism. TDP is analyzed in the clinical laboratory to assess the nutritional status of individuals at risk of deficiency. In recent years, demand for vitamin B1 testing … Read more
Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes
Clin Chem. 2025 Apr 7:hvaf035. doi: 10.1093/clinchem/hvaf035. Online ahead of print. ABSTRACT BACKGROUND: Methylglyoxal (MGO) is a potent glycating agent that contributes to the pathogenesis of diabetes. However, MGO is unstable in plasma without demanding sample preparation at blood collection, limiting its clinical utility as a biomarker. We aimed to discover reliable MGO-glycated albumin (ALB)-derived … Read more
Toward Improved Prostate Cancer Screening: Insights from the Göteborg-2 Trial
Clin Chem. 2025 Apr 4:hvaf032. doi: 10.1093/clinchem/hvaf032. Online ahead of print. NO ABSTRACT PMID:40183422 | DOI:10.1093/clinchem/hvaf032
Mannose Phosphate Isomerase Deficiency-Congenital Disorder of Glycosylation (MPI-CDG) Type 1b: Familial Case of Thrombophilia and Liver Disorder
Clin Chem. 2025 Apr 3;71(4):523-525. doi: 10.1093/clinchem/hvaf009. NO ABSTRACT PMID:40178550 | DOI:10.1093/clinchem/hvaf009
New Clinical Practice Guidelines for Vitamin D Supplementation and Testing
Clin Chem. 2025 Apr 3;71(4):526-528. doi: 10.1093/clinchem/hvae213. NO ABSTRACT PMID:40178549 | DOI:10.1093/clinchem/hvae213
Commentary on Normal Thyroid-Stimulating Hormone and Elevated Free Thyroxine in a Patient Presenting with Self-Reported Heart Palpitations
Clin Chem. 2025 Apr 3;71(4):449. doi: 10.1093/clinchem/hvae205. NO ABSTRACT PMID:40178548 | DOI:10.1093/clinchem/hvae205
Normal Thyroid-Stimulating Hormone and Elevated Free Thyroxine in a Patient Presenting with Self-Reported Heart Palpitations
Clin Chem. 2025 Apr 3;71(4):445-448. doi: 10.1093/clinchem/hvae177. NO ABSTRACT PMID:40178547 | DOI:10.1093/clinchem/hvae177
Commentary on Normal Thyroid-Stimulating Hormone and Elevated Free Thyroxine in a Patient Presenting with Self-Reported Heart Palpitations
Clin Chem. 2025 Apr 3;71(4):450. doi: 10.1093/clinchem/hvae197. NO ABSTRACT PMID:40178546 | DOI:10.1093/clinchem/hvae197
Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma
Clin Chem. 2025 Apr 2:hvaf030. doi: 10.1093/clinchem/hvaf030. Online ahead of print. ABSTRACT INTRODUCTION: The number of assays on proteomic platforms has grown rapidly. The leading platforms, SomaScan and Olink, have strengths and limitations. Comparisons of precision on the latest platforms-SomaScan 11k and Olink Explore HT-have not yet been established. METHODS: Among 102 participants in the … Read more