Wheaties
Clin Chem. 2021 Nov 1;67(11):1578. doi: 10.1093/clinchem/hvab179. NO ABSTRACT PMID:40462361 | DOI:10.1093/clinchem/hvab179
Clinical Chemistry
Everyday People
Clin Chem. 2022 Jun 1;68(6):864-865. doi: 10.1093/clinchem/hvac052. NO ABSTRACT PMID:40462370 | DOI:10.1093/clinchem/hvac052
Deconvoluting the Proteome with Confidence Using Mass Spectrometric Tools
Clin Chem. 2022 Feb 1;68(2):374-375. doi: 10.1093/clinchem/hvab250. NO ABSTRACT PMID:40462369 | DOI:10.1093/clinchem/hvab250
0/2 h-Algorithm for Rapid Triage of Suspected Myocardial Infarction Using a Novel High-Sensitivity Cardiac Troponin I Assay
Clin Chem. 2022 Feb 1;68(2):303-312. doi: 10.1093/clinchem/hvab203. ABSTRACT BACKGROUND: We aimed to derive and validate a 0/2 h-algorithm using the new high-sensitivity cardiac troponin I (hs-cTnI)-VITROS assay (VITROS® Immunodiagnostic Products hs-Troponin I Reagent Pack, Ortho Clinical Diagnostics) for rapid rule-out/in of non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: The final diagnosis was centrally adjudicated by 2 … Read more
Subclassification of Type 2 Diabetes Paves the Way for Personalized Outcome Prediction and Patient Management
Clin Chem. 2021 Mar 31;67(4):701. doi: 10.1093/clinchem/hvab003. NO ABSTRACT PMID:40462367 | DOI:10.1093/clinchem/hvab003
Robotic Process Automation in Laboratory Medicine
Clin Chem. 2025 May 28:hvaf060. doi: 10.1093/clinchem/hvaf060. Online ahead of print. NO ABSTRACT PMID:40432581 | DOI:10.1093/clinchem/hvaf060
Diagnosis of Drug-Resistant Tuberculosis: Rapid Evaluation of Drug Susceptibility with Nanopore Targeted Sequencing
Clin Chem. 2025 May 27:hvaf061. doi: 10.1093/clinchem/hvaf061. Online ahead of print. ABSTRACT BACKGROUND: Whole-genome sequencing (WGS) has limitations in clinical diagnostics due to host DNA interference and lower pathogen load in clinical samples compared to cultured isolates, which reduce the effective sequencing depth and compromise the detection of resistance-associated mutations. As our understanding of the … Read more
Reducing the Noise in Plasma Metagenomics to Further Define Clinical Utility
Clin Chem. 2025 May 26:hvaf065. doi: 10.1093/clinchem/hvaf065. Online ahead of print. NO ABSTRACT PMID:40415580 | DOI:10.1093/clinchem/hvaf065
Full-Length Clonal Immunoglobulin Rearrangements in cfDNA: Improved Recovery and Sequencing
Clin Chem. 2025 May 26:hvaf064. doi: 10.1093/clinchem/hvaf064. Online ahead of print. ABSTRACT BACKGROUND: Circulating tumor DNA present in cell-free DNA (cfDNA) serves as diagnostic, predictive, and prognostic markers in cancer patients. In lymphoma patients, clonal immunoglobulin (cIg) sequences enable accurate identification of disease states. Despite its importance, there is sparse literature surrounding the preanalytical and … Read more
Challenges in Hb A1c Point-of-Care Testing: Only 6 of 19 Hb A1c Point-of-Care Devices Meet IFCC and NGSP Certification Criteria on Independent Evaluation
Clin Chem. 2025 May 26:hvaf059. doi: 10.1093/clinchem/hvaf059. Online ahead of print. ABSTRACT BACKGROUND: Access to Hb A1c testing in low- and middle-income countries (LMICs) can be limited, especially in rural areas. This has led to an increased interest in the potential role of point-of-care testing (POCT) for Hb A1c. The analytical performance of many of … Read more