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Pharmacogenetics of colorectal cancer in a third-level hospital in Valencia​Ana Comes-Ragaon December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Nov 7;5(4):425-431. doi: 10.1515/almed-2024-0146. eCollection 2024 Dec. ABSTRACT OBJECTIVES: Genetic variants with associated pharmacokinetic and pharmacodynamic effects have an impact on the development of adverse drug reactions and survival of patients with colorectal cancer. METHODS: A selection of genetic variants was performed according to the established chemotherapy and the pharmacogenetic databases. … Read more

Comparison between a new device for the semen quality analysis and the manual microscopic evaluation in a not specialistic clinical laboratory​Erika Janion December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Aug 26;5(4):402-406. doi: 10.1515/almed-2024-0089. eCollection 2024 Dec. ABSTRACT OBJECTIVES: Semen analysis investigates different parameters of human semen with a high relevance in fertility workup, confirmation of sterility by post vasectomy, in pathologies follow-up such as varicocele and in all cases where sperm preservation is required. Manually seminal fluid examination is characterized … Read more

Estudio sobre el valor incremental que supone el informe del sedimento en orina en medicina de urgencias mediante el sistema Sysmex® Serie-UN​Marco Tosion December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Nov 26;5(4):381-385. doi: 10.1515/almed-2024-0181. eCollection 2024 Dec. ABSTRACT OBJETIVOS: El análisis de orina es ampliamente utilizado y frecuentemente solicitado desde los servicios de urgencias para evaluar la presencia de hipovolemia, infecciones del tracto urinario, diabetes, cetoacidosis y hematuria. Nuestro objetivo era evaluar el impacto de informar el sedimento urinario en muestras … Read more

Los análisis de orina en el diagnóstico de las gammapatías monoclonales: puntos de corte​Mònica Vidal-Plaon December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Dec 10;5(4):443-446. doi: 10.1515/almed-2024-0184. eCollection 2024 Dec. ABSTRACT OBJETIVOS: Las pruebas de laboratorio resultan cruciales en el diagnóstico de las gammapatías monoclonales. La última actualización de la guía del Grupo Internacional de Trabajo sobre el Mieloma (IMWG) para el diagnóstico de gammapatías monoclonales ha suscitado cierto debate sobre la pertinencia de … Read more

Falso valor de HbA1c debido a la variante inusual hemoglobina Petie Salpetriere coheredada con talasemia alfa​Esperanza Lepe Balsalobreon December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Nov 8;5(4):451-454. doi: 10.1515/almed-2024-0143. eCollection 2024 Dec. ABSTRACT OBJETIVOS: Describir la variante de hemoglobina que interfiere en el análisis de HbA1c mediante HPLC de intercambio catiónico. CASO CLÍNICO: Paciente de 78 años que acude a consulta de Medicina Interna para una revisión rutinaria, donde se incluye la determinación de HbA1c para … Read more

Investigating the incremental value of urine sediment reporting in emergency medicine with a Sysmex UN urinalysis system​Marco Tosion December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Jul 12;5(4):377-380. doi: 10.1515/almed-2024-0035. eCollection 2024 Dec. ABSTRACT OBJECTIVES: Urinalysis is widely used and is also frequently requested in emergency situations for screening hypovolemia, urinary tract infections, diabetes, ketoacidosis and hematuria. Our aim was to evaluate the impact of reporting urinary sediment in emergency department specimens with the Sysmex UN system. … Read more

Impacto de la mutación T315I en el pronóstico de la leucemia mieloide crónica​Bushra Kaleemon December 23, 2024 at 11:00 am

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Adv Lab Med. 2024 Nov 27;5(4):418-424. doi: 10.1515/almed-2024-0172. eCollection 2024 Dec. ABSTRACT OBJETIVOS: Las mutaciones dominio quinasa BCR-ABL1 son una de las principales causas de resistencia a los inhibidores de la tirosina quinasa (ITK) en la leucemia mieloide crónica (LMC), siendo la mutación T315I la más resistente a tratamiento. El objetivo del presente estudio es … Read more

Isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedures for the quantification of 24(R),25-dihydroxyvitamin D2 and 24(R),25-dihydroxyvitamin D3 in human serum and plasmaKerstin Kandleron March 5, 2025 at 11:00 am

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Clin Chem Lab Med. 2025 Mar 6. doi: 10.1515/cclm-2024-1139. Online ahead of print. ABSTRACT OBJECTIVES: Isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC MS/MS)-based candidate reference measurement procedures (RMPs) for the quantification of 24,25(OH)2D2 and 24,25(OH)2D3 in human serum and plasma are presented. METHODS: Quantitative nuclear magnetic resonance (qNMR) spectroscopic methodology was utilized to assign absolute content … Read more

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