Evaluation of an alternative centrifugation protocol for reducing total turnaround time​Reyes Nicolás de Blason March 31, 2025 at 10:00 am

Adv Lab Med. 2024 Nov 21;6(1):108-112. doi: 10.1515/almed-2024-0170. eCollection 2025 Mar. ABSTRACT OBJECTIVES: Centrifugation is a key process that should be controlled to ensure an adequate sample quality. To achieve rapid, standardized, and consistent sample centrifugation, we aimed to evaluate an alternative centrifugation protocol and its impact on the results of 20 biochemical determinations in … Read more

Reference intervals of hematological parameters in the Chilean adult population and the Mapuche ethnic group​Pablo J Letelieron March 31, 2025 at 10:00 am

Adv Lab Med. 2025 Jan 3;6(1):59-68. doi: 10.1515/almed-2024-0080. eCollection 2025 Mar. ABSTRACT OBJECTIVES: Reference intervals (RI) are an essential tool to support clinical decisions. These may have intra- and inter-individual variations associated with genetic differences and environmental factors. Given that Chile is a multiethnic territory, studying these variables is even more relevant. The purpose of … Read more

Evaluating seven bioinformatics platforms for tertiary analysis of genomic data from whole exome sequencing in a pilot group of patients​Nerea Bastida-Lertxundion March 31, 2025 at 10:00 am

Adv Lab Med. 2025 Mar 10;6(1):28-36. doi: 10.1515/almed-2025-0031. eCollection 2025 Mar. ABSTRACT OBJECTIVES: To evaluate seven bioinformatics platforms for automated AI-based genomic variant prioritization and classification. METHODS: An evaluation was performed of 24 genetic variants that explained the phenotype of 20 patients. FASTQ files were simultaneously uploaded on the following bioinformatics platforms: Emedgene, eVai, Varsome … Read more

Evaluating the research parameters available on the Sysmex® XN-series hematology analyzers as markers of dysplasia in peripheral blood​Vicente Aguaderoon March 31, 2025 at 10:00 am

Adv Lab Med. 2025 Feb 4;6(1):98-102. doi: 10.1515/almed-2025-0003. eCollection 2025 Mar. ABSTRACT OBJECTIVES: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by peripheral blood cytopenias, cellular dysplasia and risk for progression into acute leukemia. Recent studies reveal that some research parameters available on Sysmex XN-1000® hematology analyzers, including immature platelet fraction (IPF), Neutrophil Granularity Index … Read more

Parameters of glycemic variability in continuous glucose monitoring as predictors of diabetes: a prospective evaluation in a non-diabetic general population​Javier Rodríguez Garcíaon March 31, 2025 at 10:00 am

Adv Lab Med. 2025 Mar 7;6(1):46-51. doi: 10.1515/almed-2025-0011. eCollection 2025 Mar. ABSTRACT OBJECTIVES: To prospectively examine the ability of some glycemic variability metrics from continuous glucose monitoring (CGM) to predict the development of diabetes in a non-diabetic population. METHODS: A total of 497 non-diabetic patients from the AEGIS study were included. Participants used a CGM … Read more

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