Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Patipat Rachawangmuang, Patutong Chatchawal, Patcharaporn Tippayawat, Apinya Jusakul, Ratthapol Kraiklang, Worachart Lert-itthiporn, Anuchin Najermploy, Molin Wongwattanakul
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Yanling Zhao, Minghua Zhan, Jianing Chen, Honglin Xu, Futai Feng, Zhou Bai, Fang Wang, Yongjing Cheng, Xuan Zhang, Yudong Liu
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Abdurrahman Coskun, Hikmet Can Çubukçu
Clin Chem Lab Med. 2025 Oct 20. doi: 10.1515/cclm-2025-0938. Online ahead of print. ABSTRACT OBJECTIVES: Automated urine particle analyzers are increasingly employed in clinical laboratories to standardize urinalysis. These systems can reduce workload, turnaround time and the inter-observer variation. This study aimed to assess the performance of five automated urine particle analyzers in detecting and … Read more
Clin Chem Lab Med. 2025 Oct 20. doi: 10.1515/cclm-2025-1032. Online ahead of print. ABSTRACT With the advent of flow cytometry and dedicated fluorescent dyes in the 1980s, automated reticulocyte enumeration has effectively superseded conventional manual microscopy, dramatically boosting throughput and precision while, through metrics including the immature reticulocyte fraction (IRF) and reticulocyte production index (RPI), … Read more
Publication date: December 2025 Source: Clinical Biochemistry, Volume 140 Author(s): Tiziana Zangardi, Sara Altinier, Monica Maria Mion, Michele Cennamo, Ada Aita, Silvia Bressan, Daniela Basso
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Nick Flynn, Stuart J. Moat, Sarah L. Hogg
Clin Chem. 2025 Oct 14:hvaf123. doi: 10.1093/clinchem/hvaf123. Online ahead of print. ABSTRACT The European Union (EU) In Vitro Diagnostic Regulation (IVDR) imposes stringent obligations on laboratories using in-house in vitro diagnostic devices (IH-IVDs), yet offers limited clarity on whether discrete work flow steps may be subcontracted while maintaining compliance with Article 5(5). This Special Report … Read more
Clin Chem. 2025 Oct 14:hvaf116. doi: 10.1093/clinchem/hvaf116. Online ahead of print. ABSTRACT BACKGROUND: This study simulates how assay-specific bias influences the diagnostic performance of 0/1-h accelerated diagnostic protocols (ADPs) for 3 different high-sensitivity cardiac troponin (hs-cTn) assays. METHODS: We included 1493 patients presenting with chest pain. hs-cTnT (Roche Diagnostics), hs-cTnI from Abbott Diagnostics (hs-cTnI-A), and … Read more
Clin Chem Lab Med. 2025 Oct 16. doi: 10.1515/cclm-2025-1220. Online ahead of print. ABSTRACT The pre-analytical phase of laboratory testing, encompassing processes from test ordering to sample analysis, represents the most error-prone component of laboratory medicine, accounting for 68-98 % of laboratory mistakes. These errors compromise patient safety, increase healthcare costs, and disrupt operational efficiency. … Read more
