Journal – Page 5 – Clinical Chemistry INFO

T-cell receptor beta constant 1 flow cytometry for diagnosing clonality in mature T-cell neoplasms: a systematic review and meta-analysis of diagnostic accuracyPablo Adrian Biaggionion February 19, 2026 at 11:00 am

February 20, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Feb 20. doi: 10.1515/cclm-2025-1376. Online ahead of print. ABSTRACT INTRODUCTION: Accurate assessment of T-cell clonality is key for diagnosing mature T-cell neoplasms. TRBC1-based flow cytometry provides a rapid, robust, and cost-efficient approach. This systematic review and meta-analysis assessed the diagnostic accuracy of TRBC1 flow cytometry (TRBC1-FC) for detecting T-cell clonality … Read more

Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

February 19, 2026 by ccinfoadmin

Clin Chem. 2026 Feb 19:hvag005. doi: 10.1093/clinchem/hvag005. Online ahead of print. ABSTRACT BACKGROUND: The provision of prenatal genetic screening in 3 core clinical contexts-recessive conditions, aneuploidy, and serological incompatibility-involves multiple tests across reproductive partners. This complexity limits utilization and impairs adherence to guideline-recommended care, particularly in carrier screening, where male partners are frequently not tested … Read more

Applying the OMOP common data model to laboratory data: challenges, opportunities, and implications – a use case in biological variation researchBlanca Beumer Prietoon February 19, 2026 at 11:00 am

February 19, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Feb 20. doi: 10.1515/cclm-2025-1668. Online ahead of print. NO ABSTRACT PMID:41711567 | DOI:10.1515/cclm-2025-1668

Indirect reference intervals for thyroid function tests: refineR, RefLim and effects of pathological test resultson February 19, 2026 at 12:22 pm

February 19, 2026 by ccinfoadmin

Publication date: March 2026 Source: Clinical Biochemistry, Volume 142 Author(s): Finn Erik Aas, Alexander Bauer Westbye, Magnus A.R. Husøy, Oskar E. Kelp, Svetlana N. Zykova, Per M. Thorsby

The 22q11.2 deletion syndrome: Genetic mechanisms, clinical manifestations, and therapeutic strategieson February 19, 2026 at 12:22 pm

February 19, 2026 by ccinfoadmin

Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Shaozhe Yang, Yuan Zhuang, Shuwen Xin, Yanqi He, Xiuhong Fu

CYFRA 21-1 as a circulating biomarker in non-small cell lung canceron February 19, 2026 at 12:22 pm

February 19, 2026 by ccinfoadmin

Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Neelam Singla, Kavita Goyal, Pawan Goud, Vaishali Goel, Avijit Mazumder, K.P. Hemalatha, Vijayakumar Sachidananda, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, Brian Gregory George Oliver

Artificial intelligence and machine learning applications in dialysis: Current applications, challenges, and future directionson February 19, 2026 at 12:22 pm

February 19, 2026 by ccinfoadmin

Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Aanuoluwapo Clement David-Olawade, Muyiwa Ademola Ogunbona, Olabanke Florence Olawuyi, Babajide David Makanjuola, John Oluwatosin Alabi, David B. Olawade

Interference and failure: The challenge of high-concentration IgM monoclonal protein in capillary zone electrophoresison February 18, 2026 at 5:42 pm

February 18, 2026 by ccinfoadmin

Publication date: March 2026 Source: Clinical Biochemistry, Volume 142 Author(s): Yanhua Zhao, Minjie Zhang, Wei Gan

Machine learning in precision oncology: a rough diamond waiting to shine?Sander De Bruyneon February 18, 2026 at 11:00 am

February 18, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Feb 6. doi: 10.1515/cclm-2025-1706. Online ahead of print. NO ABSTRACT PMID:41704195 | DOI:10.1515/cclm-2025-1706

An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of testosterone in human serum and plasmaElie Fuxon February 18, 2026 at 11:00 am

February 18, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Feb 6. doi: 10.1515/cclm-2024-1266. Online ahead of print. ABSTRACT OBJECTIVES: This study presents a candidate reference measurement procedure (RMP) for testosterone quantification in human serum and plasma, utilizing isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC MS/MS). METHODS: The developed LC-MS/MS method employs a two-dimensional heart-cut LC approach combined with solid-phase extraction … Read more