Limitations to the development of Milan model 1b analytical performance specificationsGraham Ross Dallas Joneson May 9, 2026 at 10:00 am

Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0377. Online ahead of print. ABSTRACT A widely accepted approach to setting Analytical Performance Specifications (APS) in laboratory medicine is the Milan models. Milan model 1b is an approach where APS are developed based on patient classification, or clinical decision-making, noting that these factors link to the … Read more

Factors associated with analytical errors in blood chemistry testsHyunjung Kimon May 9, 2026 at 10:00 am

Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0153. Online ahead of print. ABSTRACT OBJECTIVES: Few studies have systematically evaluated the factors contributing to laboratory errors in the analytical phase. This study analyzed five years of retest data to determine the frequency and characteristics of analytical errors across routine blood chemistry parameters, identify analytes most … Read more

Rapid and highly sensitive detection of MYD88/CXCR4 mutations in Waldenström macroglobulinemia by MAS-qPCR: A pilot study​​on May 11, 2026 at 2:32 pm

Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Yuki Kunimune, Mitsuaki Nishioka, Haruka Namba, Kimika Todaka, Tomohiro Fujii, Nayu Kiso, Yukiko Nakahara, Kanae Shinkawa, Yumiko Kumano, Masaki Kodama, Tomoya Ebisui, Ryoga Nishimoto, Naoko Okayama, Yutaka Suehiro, Takahiro Yamasaki, Toshiaki Yujiri

Analytical agreement and platform-specific decision thresholds for plasma p-tau217 measured on Lumipulse G600II and Cobas e801 in a paired CSF-plasma cohortMaría Martínez-Bujidoson May 5, 2026 at 10:00 am

Clin Chem Lab Med. 2026 May 5. doi: 10.1515/cclm-2026-0395. Online ahead of print. ABSTRACT OBJECTIVES: Plasma phosphorylated tau at threonine 217 (p-tau217) has emerged as a highly accurate blood-based biomarker of Alzheimer’s disease (AD) pathology. As disease-modifying anti-amyloid therapies enter clinical practice, scalable biomarkers with robust and clinically interpretable decision thresholds are required. However, evidence … Read more

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