In Reply to Inter-Instrument Imprecision Complements Bias in Evaluating LDL-C Method Performance
Clin Chem. 2026 May 7:hvag043. doi: 10.1093/clinchem/hvag043. Online ahead of print. NO ABSTRACT PMID:42095830 | DOI:10.1093/clinchem/hvag043
Journal
Pseudovirus reference material and RT-digital PCR reference method for the quantification of human rhinovirus RNA with metrological traceabilityHuijie Lion May 6, 2026 at 10:00 am
Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2025-1137. Online ahead of print. ABSTRACT OBJECTIVES: This study developed a pseudoviral human rhinovirus (HRV) reference material using pseudovirus technology and integrating RT-dPCR with HPLC-IDMS to achieve accurate HRV RNA quantification, aiming to standardize HRV detection across labs and platforms. METHODS: We developed an RT-digital PCR (RT-dPCR) … Read more
EFLM position statement on the proposed 2025/0404(COD) IVDR Amendment of Article 5.5Christa Cobbaerton May 6, 2026 at 10:00 am
Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2026-0580. Online ahead of print. ABSTRACT Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR) was introduced to enhance patient safety and ensure the availability of safe and effective diagnostics across the European Union. However, its implementation has led to substantial unintended consequences, including certification bottlenecks, … Read more
From research to reality: real-world effectiveness of point-of-care testing in the emergency departmentSalomón Martin-Pérezon May 5, 2026 at 10:00 am
Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0289. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate the real-world impact of Point-of-Care Testing on care timeliness and patient flow in the emergency department. METHODS: A before-and-after, matched-cohort study was conducted involving 25,291 patients with Emergency Severity Index levels 3-4. A POCT group (n=8,746) was compared … Read more
Corrigendum to “Biological variability of lipoprotein-associated phospholipase A2 activity in healthy individuals” [Clin. Biochem. 50 (2017) 347–349]on May 10, 2026 at 5:20 am
Publication date: June 2026 Source: Clinical Biochemistry, Volume 143 Author(s): Leslie J. Donato, Jeffrey W. Meeusen, Sarah M. Jenkins, Stacy J. Hartman, Amy K. Saenger, Nikola A. Baumann, Darci R. Block, Allan S. Jaffe
Multi-omics identification of aging-related diagnostic genes and therapeutic targets in renal fibrosison May 10, 2026 at 5:20 am
Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Supei Yin, Jiaojiao Gong, Dongli Huang, Diguang Wen, Zhihui Quan, Chengmei Shu
The role of coagulation waveform kinetic parameters in the early diagnosis and prognosis of coagulopathy in hepatitis and cirrhosison May 10, 2026 at 5:20 am
Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Qinglan Lu, Weijie Zhou, Min Pan, Shuliang Hua, Dongrong Luo, Lina Yang, Xiaoxuan Zhou, Jinjiu Huang, Rukai Wu, Xiaomei Huang, Shuzhen Liao, Xiaoli Ni, Danning Mo, Xiannian Shao, Jianghui Dong, Liping Wang
Harmonizing sample collection quality indicator monitoring via an informatics platform in a regional medical laboratory networkon May 10, 2026 at 5:20 am
Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Dayang Chen, Yingying Zhang, Liya Liu, Ruiwei Jiang, Qingshan Ma, Hui Wu, Xiuming Zhang, Tong Ou
Automated ICAP AC-30/AC-2 discrimination on HEp-2 indirect immunofluorescence: development and clinical validation of a retrieval-based diagnostic systemon May 10, 2026 at 5:20 am
Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Changmeng Wu, Kechi Fang, Chuan Li, Yu Li, Jing Wang
Free light chain EQA: Analytical variability with clinical consequences – Data from 25 Italian EQA exercises (2021–2025)on May 10, 2026 at 5:20 am
Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Fabio Pasotti, Simona Da Molin, Tiziana Bosoni, Giovanna Azzarà, Giuseppa Liga, Giuseppe Moriello, Barbara Zaccaria, Sabrina Buoro