Journal

Ultra-trace urinary clostebol findings: should delayed transfer from contaminated objects be considered?Alberto Salomoneon August 27, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Aug 28. doi: 10.1515/cclm-2026-1235. Online ahead of print. ABSTRACT Clostebol is an anabolic androgenic steroid prohibited at all times (class S1.1) by the World Anti-Doping Agency. In several countries, however, clostebol acetate is available without prescription in topical medicinal products, particularly Trofodermin®, creating a substantial risk of inadvertent exposure. Experimental … Read more

From metrological comparability to clinical continuity: authorising laboratory result reporting when changing measurement proceduresRaúl Rigo-Bonninon August 27, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Aug 27. doi: 10.1515/cclm-2026-1271. Online ahead of print. ABSTRACT OBJECTIVES: To develop and apply an operational framework integrating metrological, analytical, clinical and risk evidence to authorise an output-specific reporting rule after a change in measurement procedure. METHODS: Four measurement procedure changes were evaluated: alanine aminotransferase (ALT) procedures with and without … Read more

Clinical Utility and Diagnostic Performance of (1→3)-β-D-Glucan in Invasive Mycoses

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Clin Chem. 2026 Aug 26:hvag108. doi: 10.1093/clinchem/hvag108. Online ahead of print. ABSTRACT BACKGROUND: The BDG assay is a non-culture-based biomarker widely used in the diagnosis of invasive fungal infections, particularly among immunocompromised patients. Conventional diagnostic methods, including culture and histopathology, are limited by low sensitivity and delayed turnaround times, prompting increased reliance on adjunctive serologic … Read more

Diagnostic accuracy of dried blood spot samples for hepatitis B diagnosis: a systematic review and meta-analysisSonghe Wangon August 26, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Aug 26. doi: 10.1515/cclm-2026-1075. Online ahead of print. ABSTRACT INTRODUCTION: Hepatitis B virus (HBV) infection remains a major global public health problem. Dried blood spot (DBS) sampling is simple to collect, stable during transport, and easy to store, and may therefore provide an alternative sampling strategy for decentralized HBV testing. … Read more

Genetic Investigation of X-Linked Defects with Optimized Targeted Long-Read Sequencing

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Clin Chem. 2026 Aug 24:hvag088. doi: 10.1093/clinchem/hvag088. Online ahead of print. ABSTRACT BACKGROUND: X-linked genetic diseases affect males and females through different inheritance patterns influenced by sex, where differential methylation caused by X-chromosome inactivation can present with a range of asymptomatic, mild, and severe symptoms in females. Targeted long-read sequencing (LRS) through adaptive sampling (AS) … Read more

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