Precision Medicine for Lipids: The New US Guidelines for Dyslipidemia
Clin Chem. 2026 Jul 15:hvag083. doi: 10.1093/clinchem/hvag083. Online ahead of print. NO ABSTRACT PMID:42455123 | DOI:10.1093/clinchem/hvag083
Journal
Characterization of the Migration Profile of 36 Therapeutic Monoclonal Antibodies in Serum Protein Electrophoresis and Immunofixation
Clin Chem. 2026 Jul 15:hvag080. doi: 10.1093/clinchem/hvag080. Online ahead of print. ABSTRACT BACKGROUND: Therapeutic monoclonal antibodies (t-mAbs) are widely used in oncology, hematology, and immune-mediated diseases. Some t-mAbs are detectable by serum protein electrophoresis (SPEP) and immunofixation (IF), potentially mimicking monoclonal gammopathies. Despite widespread use, migration profiles of many t-mAbs remain incompletely described. METHODS: Thirty-six … Read more
A markedly increased CK-MB relative index suggests a skeletal muscle contribution to re-elevated troponin T in immune checkpoint inhibitor-associated myositisYoko Usamion July 15, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jul 16. doi: 10.1515/cclm-2026-0936. Online ahead of print. NO ABSTRACT PMID:42453044 | DOI:10.1515/cclm-2026-0936
Venous-capillary blood agreement for routine chemistry analytes: effects of collection site and sample matrixSara Dezaon July 14, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jul 15. doi: 10.1515/cclm-2026-0671. Online ahead of print. ABSTRACT OBJECTIVES: Capillary blood sampling enables minimally invasive testing and decentralized workflows, but interchangeability with venous specimens may depend on collection site, device, and matrix. METHODS: We conducted a single-center, paired clinical study of 480 adults yielding 960 capillary specimens (fingertip lancet … Read more
Chemometric profiling reveals selective circulating bile acid remodeling in Alzheimer’s diseaseon July 14, 2026 at 12:03 pm
Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): M. Emam, Fatema S. Alatawi, Yasser Alzamil, Nisreen Haj, Amani A. Mahbub, Amna Mohamed Ahmed, Sara Albadri, Malik Bader Alazzam, For the Alzheimer’s Disease Neuroimaging Initiative
Flow cytometric analysis of peritoneal dialysis fluid in suspected peritonitis: diagnostic performance and limitationsLea Tybirkon July 13, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jul 14. doi: 10.1515/cclm-2026-0684. Online ahead of print. ABSTRACT OBJECTIVES: Peritonitis is a feared complication to peritoneal dialysis (PD), requiring empirical broad-spectrum antibiotics. A rapid method to predict culture positivity and bacterial Gram classification could enable earlier targeted therapy and reduce unnecessary antibiotic exposure. This study evaluated the diagnostic performance … Read more
Performance of the CellaVision advanced RBC application for schistocyte counting in the emergency clinical laboratoryElisa Pivaon July 13, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jul 14. doi: 10.1515/cclm-2026-0463. Online ahead of print. ABSTRACT OBJECTIVES: Schistocyte quantification is essential for diagnosing microangiopathic hemolytic anemia (MAHA) and thrombotic microangiopathies (TMA). Early exclusion is critical for guiding appropriate management. However, the reference standard remains time-consuming manual microscopy, highly operator-dependent. In this study, the CellaVision Advanced RBC Application … Read more
Evaluating a custom GPT assistant for critical appraisal of biological variation studies by the BIVACJorge Díaz-Garzón Marcoon July 13, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jul 14. doi: 10.1515/cclm-2026-1049. Online ahead of print. NO ABSTRACT PMID:42441760 | DOI:10.1515/cclm-2026-1049
Development and validation of patient-based exponentially weighted moving average quality control models for three antipsychotic drugs and their metabolites by LC-MS/MSon July 13, 2026 at 11:21 am
Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Qi Guo, Yungang Pu, Jing He, Sihai Ling, Canjun Ruan, Guixin Guo, Chunyan Zhou, Chengeng Liu, Xiangyi Liu
NT-IGFBP-4: A novel biomarker for risk prediction in acute heart failureon July 12, 2026 at 10:52 am
Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Ling Li, Jing Wang, Chen Chen, Yu Wu, Juan Yang, Xin Shu, Litao Zhang, Yi Zhang, Zhenlu Zhang