Clinical Labs: Working with planetary health for patient healthon January 25, 2026 at 2:32 pm
Publication date: Available online 24 January 2026 Source: Clinical Biochemistry Author(s): Andre Mattman, Janet Simons
Journal
Analytical performance evaluation and reference limits establishment of a new chemiluminescence growth stimulation expressed Gene 2 Assayon January 25, 2026 at 12:26 pm
Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Litao Zhang, Chenbin Zhang, Xin Shu, Jiajia Zhu, Hui Wang, Ting Deng, Yisha Jing, Haiyan Liu, Zhenlu Zhang
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasmaLea Lewinon January 24, 2026 at 11:00 am
Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-1155. Online ahead of print. ABSTRACT OBJECTIVES: 5α-dihydrotestosterone (DHT) is a potent androgen, related to male sexual development and irreversibly synthesized from testosterone via 5α-reductase. Dysfunctions in the 5α-reductase system, locally or globally, can have substantial health impacts; measurement of both DHT levels and the testosterone-DHT ratio … Read more
Validating CALIPER pediatric reference intervals in a U.S. population using retrospective outpatient data and RefineRon January 24, 2026 at 5:32 pm
Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Jillian Kodger, Thomas J.S. Durant, Nalan Yurtsever, Joe M. El-Khoury
Biological variation and inter-relation between key calcium homeostasis biomarkersNora Alicia Guldhaugon January 23, 2026 at 11:00 am
Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-1225. Online ahead of print. ABSTRACT OBJECTIVES: This study aims to explore the biological variability of calcium homeostasis biomarkers, including calcium, phosphate, magnesium, 25-OH vitamin D, 1,25-OH vitamin D, and parathyroid hormone (PTH), and to develop a model that predicts PTH concentrations based on these parameters. METHODS: … Read more
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of voriconazole in human serum and plasmaMarie Kubicovaon January 23, 2026 at 11:00 am
Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-1371. Online ahead of print. ABSTRACT OBJECTIVES: Voriconazole is an antifungal agent measured in serum and plasma for therapeutic drug monitoring. This study aimed to develop a robust isotope-dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) reference measurement procedure (RMP) to ensure accurate and reliable quantification in compliance with … Read more
Acquired bisalbuminemia: A case reporton January 23, 2026 at 12:30 pm
Publication date: Available online 22 January 2026 Source: Clinical Biochemistry Author(s): R. Addesso, S. Sarpa, M. Ferrandino, C. Giorgione, A. Marrone, M. Savoia, G. Castaldo
Comparison of six serum analyte workflows using routine liquid chromatography-tandem mass spectrometry methods at multiple laboratories with the Cobas i 601 analyzer, an automated mass spectrometry systemPieter Vermeerschon January 23, 2026 at 11:00 am
Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-0994. Online ahead of print. ABSTRACT OBJECTIVES: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) offers substantial analytical advantages over traditional immunoassay methods, including greater specificity and robustness. Conventional LC-MS/MS methods are labor-intensive, requiring highly trained, dedicated laboratory staff. The Cobas® i 601 analyzer (Roche Diagnostics International Ltd., Rotkreuz, Switzerland) … Read more
ALT-triggered reflex AST testing in health check-ups: A decision curve analysison January 22, 2026 at 9:35 am
Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Shu-Mei Bai, Xu-Xiao Guo, Guo-Ming Zhang
Exosome biosensors for detection of Lung canceron January 22, 2026 at 9:35 am
Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Obaid Afzal, Pavan Goud, Kavita Goyal, Ali Altharawi, Mubarak A. Alamri, Manal A. Alossaimi, Abdulmalik S.A. Altamimi, Surya Nath Pandey