Journal

Real-world performance of Lumipulse G plasma p-tau217: a six-month experience of a specialized clinical neurochemistry laboratoryBurak Arslanon April 29, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0370. Online ahead of print. ABSTRACT OBJECTIVES: Plasma p-tau217 is a leading blood-based biomarker for Alzheimer’s disease (AD), offering high diagnostic accuracy and potential utility for treatment eligibility and monitoring. However, real-world data on concordance between cerebrospinal fluid (CSF) Aβ42/40 and plasma p-tau217 in routine clinical laboratory … Read more

Clinical validation and implementation of mSTOP, a machine learning-based, longitudinal prediction model for the early identification of non-small cell lung cancer patients who not benefit from immune checkpoint inhibitor treatmentHuub H van Rossumon April 29, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1624. Online ahead of print. ABSTRACT OBJECTIVES: There has been a lot of interest in the field of laboratory medicine regarding the use of machine learning (ML)-based prediction models. The longitudinal ML-based Serum Tumor marker-based Outcome Prediction (STOP) model was previously developed to identify non-small cell lung … Read more

Poor Performance of LDL-Cholesterol Equations versus Beta Quantification in a Very Large Cohort of Patients with Dyslipidemia

by

Clin Chem. 2026 Apr 28:hvag038. doi: 10.1093/clinchem/hvag038. Online ahead of print. ABSTRACT BACKGROUND: Accurate estimations of low-density lipoprotein cholesterol (LDL-C) is important to guide clinical decisions concerning lipid-lowering treatment. The Friedewald formula has been used for the past 50 years, but its limitations compared to the reference β-quantification method have led to the development of … Read more

Saliva vs Plasma in Liquid Biopsy Sampling for Head and Neck Cancer: A Comparative Study

by

Clin Chem. 2026 Apr 28:hvag035. doi: 10.1093/clinchem/hvag035. Online ahead of print. ABSTRACT BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) presents significant diagnostic and therapeutic challenges due to its rising incidence and poor prognosis. Liquid biopsy, utilizing biofluids such as blood and saliva, offers a noninvasive approach to detect circulating tumor DNA (ctDNA), circulating tumor … Read more

deneme bonusu veren siteler - canlı bahis siteleri - casino siteleri casino siteleri deneme bonusu veren siteler canlı casino siteleri error code: 520