Journal

Assessing the performance of EWMA and CUSUM algorithms in patient-based real-time quality control of electrolytesÖzlem Doğanon March 19, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Mar 20. doi: 10.1515/cclm-2026-0049. Online ahead of print. ABSTRACT OBJECTIVES: Patient-based real-time quality control (PBRTQC) represents a useful complement to traditional internal quality control methods, particularly in the continuous monitoring of routine analyses. Sodium, potassium, chloride, calcium, phosphorus, and magnesium are critical for patient safety. This study aimed to evaluate … Read more

The urine examination: a modern technological test with a very ancient history​Massimo Daveson March 19, 2026 at 10:00 am

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Adv Lab Med. 2025 Sep 1;7(1):10-15. doi: 10.1515/almed-2025-0121. eCollection 2026 Mar. ABSTRACT For centuries, the only ‘semeiological and laboratory’ test that the physician had at his disposal to point towards to a diagnosis was the urine test. It was based on the chemical and physical properties evaluation of the sample. During the last decade of … Read more

Non-invasive comparative study of HLA genotyping between urinary and blood DNA using sequencing-based typing and third-generation sequencing​Cheng Yan Fanon March 19, 2026 at 10:00 am

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Adv Lab Med. 2025 Dec 8;7(1):52-58. doi: 10.1515/almed-2025-0087. eCollection 2026 Mar. ABSTRACT OBJECTIVES: To evaluate the feasibility of urinary DNA as a noninvasive alternative for high-resolution HLA genotyping and validate its concordance with conventional blood-based methods. METHODS: Matched urine and blood samples were collected from 11 healthy volunteers. Urinary DNA was extracted using an optimized … Read more

Comparative analysis of platelet counts using Beckman Coulter DxH-900, Mindray BC-6800 Plus, CellaVision DM9600 and the flow cytometry reference method: addressing the challenge of giant platelets​Álvaro Piedra-Aguileraon March 19, 2026 at 10:00 am

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Adv Lab Med. 2025 Nov 24;7(1):59-63. doi: 10.1515/almed-2025-0133. eCollection 2026 Mar. ABSTRACT OBJECTIVES: To evaluate the analytical performance of platelet counts obtained by impedance- and optical-based methods on the DxH-900 and BC-6800 Plus analyzers, and by digital morphology using the CellaVision DM9600, in comparison with the international reference method (IRM), in samples with thrombocytopenia and … Read more

Pericardial fluid cytology as a diagnostic tool for diffuse large B-cell lymphoma: a case report​Antonio Sierra-Riveraon March 19, 2026 at 10:00 am

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Adv Lab Med. 2025 Oct 3;7(1):68-73. doi: 10.1515/almed-2025-0107. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Primary cardiac lymphoma represents an extremely rare entity of extranodal non-Hodgkin lymphoma. CASE PRESENTATION: We report the case of a woman who presented with dyspnea, asthenia, chest pain, cough, and odynophagia. Investigations revealed a diffuse large B-cell lymphomas type primary cardiac lymphoma … Read more

Comparison of diagnostic performance of GAAD, GALAD, and ASAP scores for detecting hepatocellular carcinoma in advanced liver fibrosis patients​Alberto Izquierdo-Martínezon March 19, 2026 at 10:00 am

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Adv Lab Med. 2026 Jan 15;7(1):43-51. doi: 10.1515/almed-2025-0144. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Alpha-fetoprotein L3 (AFP-L3 %) and protein induced by vitamin K absence-II (PIVKA-II) are used in diagnostic scores such as GAAD, GALAD, and ASAP for hepatocellular carcinoma (HCC) detection. Advanced liver fibrosis (ALF) is diagnosable by the liver fibrosis index and could be … Read more

Calculation of reference intervals using an indirect approach from laboratory database​Victor Martin-Rieraon March 19, 2026 at 10:00 am

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Adv Lab Med. 2026 Feb 9;7(1):34-42. doi: 10.1515/almed-2025-0088. eCollection 2026 Mar. ABSTRACT OBJECTIVES: The establishment of reference intervals (RIs) for biochemical parameters is crucial for the accurate interpretation of laboratory test results and clinical decision-making. This study aims to evaluate the feasibility of determining RIs using an indirect approach, which analyzes routine clinical samples instead … Read more

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