Journal – Page 22 – Clinical Chemistry INFO

Clinical validation of an automated extraction protocol and liquid chromatography single quadrupole mass spectrometry (LC-MS) method for plasma vitamins A and E analysisRowan Hellieron July 10, 2026 at 10:00 am

July 10, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0108. Online ahead of print. ABSTRACT OBJECTIVES: Quantitation of plasma vitamins A and E is essential for assessing nutritional status. Traditional methods typically involve liquid-liquid extraction followed by high-performance liquid chromatography with UV detection (HPLC-UV). In this study, we evaluated an automated sample extraction-method paired with liquid … Read more

Impact of a computerized intervention to optimize laboratory tests ordering: one-year follow-up in a geriatric unitEdith Rengueton July 10, 2026 at 10:00 am

July 10, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0938. Online ahead of print. ABSTRACT OBJECTIVES: Approximately 30 % of laboratory tests are ordered inappropriately, substantially impacting patient care, costs, and carbon footprint of laboratories. Predefined laboratory test panels are a pragmatic and routinely used tool in laboratories, where tests are bundled for efficiency to diagnose … Read more

Serum sialic acid is independently associated with cerebrovascular atherosclerotic stenosis severity and total vascular burden: A retrospective cohort studyon July 10, 2026 at 9:56 am

July 10, 2026 by ccinfoadmin

Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Qi Cai, Chunjiao Yang, Lei Luo, Yinfei Huang, Yu Xie, Xin Liang, Renwei Zhang, Yumin Liu

Serum IgG, definite anti-dsDNA positivity, and advanced HBV-related liver disease: a laboratory-based retrospective studyon July 10, 2026 at 9:56 am

July 10, 2026 by ccinfoadmin

Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Hui Chen, Xue Han, Chen Qian, Shuo Jiang, Guojun Zheng, Zhou Zhang

A follow-up cohort study on secondary findings in cancer predisposition genes from 20,205 Chinese individualson July 10, 2026 at 9:56 am

July 10, 2026 by ccinfoadmin

Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Jiaqi Xu, Jin Sun, Jie Tang, Wan Huai, Yijin Gao, Ruen Yao, Tingting Yu

Laboratory Medicine for SocietyTomáš Zimaon July 9, 2026 at 10:00 am

July 10, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0977. Online ahead of print. ABSTRACT This collective opinion paper, based on presentations delivered during the two-day European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference 2026, “Laboratory Medicine for Society” (Prague, Czech Republic, 24-25 April 2026) offers a forward-looking overview of the Federation’s strategic … Read more

What are the correlates of laboratory productivity in clinical laboratories in the Asia Pacific region?on July 9, 2026 at 1:41 pm

July 9, 2026 by ccinfoadmin

Publication date: October 2026 Source: Clinical Biochemistry, Volume 145 Author(s): Tony Badrick, Wu Ju Ting Jeanette, Zhang Hui Rebecca, Wesley Wong

Systematic bias in point-of-care INR testing: comparative analysis of Abbott and Roche devicesSandya Arunachalamon July 9, 2026 at 10:00 am

July 9, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0408. Online ahead of print. ABSTRACT OBJECTIVES: Point-of-care (POC) International Normalised Ratio (INR) testing provides rapid anticoagulation monitoring. Still, it is susceptible to systematic bias, particularly at supratherapeutic levels, which can lead to inappropriate warfarin dose adjustments and increased thrombotic risk. This study evaluated bias trends between … Read more

Introduction of new calibrator lots for quantitative protein mass spectrometry and adjustment of calibration settings for long term multiplex apolipoproteins quantificationNico P M Smiton July 8, 2026 at 10:00 am

July 9, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2025-0872. Online ahead of print. ABSTRACT OBJECTIVES: Calibration is a cornerstone of clinical chemistry test results and maintaining an in-house LDT requires periodic renewal of calibrators. Here we present the introduction of a new set of native human serum calibrators, using different curve fitting approaches for long-term … Read more

Detection of M-protein by iMS-IP and iMS-FLC assays redefines previously non-secretory POEMS syndromeYuan Huangon July 8, 2026 at 10:00 am

July 9, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0489. Online ahead of print. ABSTRACT OBJECTIVES: In polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome, when monoclonal plasma cell proliferation is absent, it is considered ‘non-secretory POEMS syndrome’. We aimed to study whether M-protein was detectable by mass spectrometry (MS) in previously non-secretory POEMS syndrome. … Read more