Publication date: Available online 8 July 2026 Source: Practical Laboratory Medicine Author(s): Yinfu Sun, Jiawen Shang, Weihong Qin, Ziyuan Peng, Miaojun Lia, Jingzhe Wang
Publication date: Available online 8 July 2026 Source: Practical Laboratory Medicine Author(s): Itsuko Miyazawa, Junko Okano, Natsuko Ohashi, Kazunori Fujino, Miwako Katagi, Shinji Kume, Hideto Kojima
Clin Chem Lab Med. 2026 Jul 9. doi: 10.1515/cclm-2026-0626. Online ahead of print. ABSTRACT OBJECTIVES: Identification of acute kidney injury (AKI) in neonatology and paediatrics continues to present challenges to laboratories. Emerging biomarkers are being developed which may offer early detection but haven’t been adopted in current guidelines yet. The aim of this IFCC survey … Read more
Clin Chem Lab Med. 2026 Jul 9. doi: 10.1515/cclm-2025-1488. Online ahead of print. ABSTRACT OBJECTIVES: Invasive prenatal diagnosis is recommended for high-risk pregnancies, but many decline due to potential complications. To date, no non-invasive prenatal testing (NIPT) simultaneously detects monogenic diseases, balanced chromosomal rearrangements (BCRs), and aneuploidies. We developed a comprehensive NIPT to detect monogenic … Read more
Clin Chem Lab Med. 2026 Jul 7. doi: 10.1515/cclm-2026-0957. Online ahead of print. ABSTRACT OBJECTIVES: Red blood cell (RBC) morphology in peripheral blood smears (PBS) remains essential for the differential diagnosis of anemia and other hematologic disorders. As yet unclassified poikilocytes, fish-shaped RBCs and pincer (mushroom-shaped) cells are rarely observed but have been described as … Read more
Clin Chem. 2026 Jul 6;72(7):814-816. doi: 10.1093/clinchem/hvag044. NO ABSTRACT PMID:42402346 | DOI:10.1093/clinchem/hvag044
Clin Chem Lab Med. 2026 Jul 6. doi: 10.1515/cclm-2026-0789. Online ahead of print. ABSTRACT Clinical laboratory medicine faces converging structural pressures: workforce shortages, growing data complexity, and rapid advances in artificial intelligence (AI). Some prominent developers, including Demis Hassabis of Google DeepMind, have projected the arrival of artificial general intelligence (AGI) around 2030; such timelines … Read more
Clin Chem. 2026 Jul 4:hvag078. doi: 10.1093/clinchem/hvag078. Online ahead of print. ABSTRACT BACKGROUND: The quantification of plasma glucagon and oxyntomodulin is important in the assessment of α-cell function, which is impaired in patients with diabetes. We aimed to transfer between laboratories a novel assay that uses liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the sensitive and … Read more
Clin Chem Lab Med. 2026 Jul 6. doi: 10.1515/cclm-2026-0743. Online ahead of print. ABSTRACT OBJECTIVES: Unified Code for Units of Measure (UCUM) encodes syntax without prescribing which unit should be used. The Nomenclature for Properties and Units (NPU) terminology, developed by IFCC and IUPAC, specifies both the kind-of-quantity (e.g., mass concentration or substance concentration) and … Read more
Clin Chem Lab Med. 2026 Jul 6. doi: 10.1515/cclm-2026-0661. Online ahead of print. ABSTRACT OBJECTIVES: The objective of this study is to evaluate the ethical dimensions of reflex and reflective testing (RRT) within the framework of value-based laboratory medicine and in alignment with ISO 15189:2022. The study aims to highlight the challenges in guiding and … Read more
