Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Zeyan Zhong, Jieni Mai, Dina Chen, Yangzong Lamu, Wenjuan Zhou, Rui Mao, Xiaoxuan Zeng, Ziyun Zhang, Junyu Deng, Xuanwei Wu, Jianhong Chen, Liang Li
Annals of Clinical Biochemistry, Ahead of Print. IntroductionWhile conclusions regarding the effects of serum separator tubes on some laboratory tests have been reached in previous studies, the effects of these tubes on the B12 test have not been adequately investigated. This study aimed to determine …
Publication date: July 2026 Source: Practical Laboratory Medicine, Volume 50 Author(s): Fouad Trad, Jana Doghman, Sarah Sayegh, Ali Chehab, Nada Assaf
Adv Lab Med. 2026 Apr 7;7(2):105-115. doi: 10.1515/almed-2025-0175. eCollection 2026 Jun. ABSTRACT OBJECTIVES: The objectives of this study included assessing the diagnostic performance of HE4 in malignant pleural effusions (MPEs) and identifying the benign etiologies associated with higher HE4 concentrations. METHODS: The study involved patients with pleural effusion (PE) treated at Part Taulí University Hospital. … Read more
Adv Lab Med. 2026 Jan 22;7(2):153-155. doi: 10.1515/almed-2025-0161. eCollection 2026 Jun. ABSTRACT OBJECTIVES: This study evaluates the efficacy of the icteric index as a pre-screening tool for hyperbilirubinemia in adult patients. METHODS: The use of this index would help optimize the use of clinical laboratory resources. RESULTS: A retrospective analysis of 3,194 serum samples revealed … Read more
Adv Lab Med. 2026 Jan 12;7(2):160-162. doi: 10.1515/almed-2025-0099. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Pulmonary-renal syndrome (PRS) is a serious condition characterized by concurrent alveolar hemorrhage and rapidly progressive glomerulonephritis. One of the potential causes of PRS is the presence of anti-glomerular basement membrane (anti-GBM) antibodies, which may induce Goodpasture syndrome, a rare, albeit life-threatening, condition … Read more
Adv Lab Med. 2025 Nov 25;7(2):156-159. doi: 10.1515/almed-2025-0148. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Troponins are a complex of three proteins that play a key role in the contraction of striated muscles. Currently, cardiac troponins T (cTnT) and I (cTnI) are the best biomarkers for acute myocardial infarction (AMI) diagnostic. CASE PRESENTATION: Immune-mediated toxicity due to … Read more
Adv Lab Med. 2026 Jan 28;7(2):81-89. doi: 10.1515/almed-2025-0187. eCollection 2026 Jun. ABSTRACT Prostate-specific antigen (PSA) is a widely available and analytically robust biomarker, but its role in prostate cancer (PCa) screening remains controversial due to concerns regarding limited specificity, overdiagnosis of indolent tumors, and the downstream risk of overtreatment. This review provides a critical analysis … Read more
Adv Lab Med. 2025 Dec 8;7(2):148-152. doi: 10.1515/almed-2025-0098. eCollection 2026 Jun. ABSTRACT OBJECTIVES: We aimed to develop a simple, cost-effective algorithm to predict the presence of oligoclonal IgM bands (OCMB) in patients with multiple sclerosis (MS), using surrogate markers such as the IgM Index (IgMi) and the Free Kappa Light Chains Index (FKLCi), with the … Read more
Adv Lab Med. 2026 Mar 16;7(2):90-104. doi: 10.1515/almed-2025-0169. eCollection 2026 Jun. ABSTRACT Carcinocythemia, or carcinoma cell leukemia, is a rare but striking manifestation of advanced malignancy in which circulating tumor cells (CTCs) are visible in peripheral blood (PB) smears using conventional staining. It is typically associated with advanced stage disease and poor prognosis. This review … Read more
