Continuous reference curves for hematology and biochemistry analytes in pregnancy – a prospective studyVesna Šupak-Smolčićon August 1, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Aug 3. doi: 10.1515/cclm-2026-0609. Online ahead of print. ABSTRACT OBJECTIVES: Pregnancy involves dynamic metabolic changes that cannot be accurately interpreted using population reference intervals (RI). The aim was to develop continuous reference curves for common hematology and biochemistry laboratory analytes in pregnancy and to assess their agreement with the RIs … Read more

Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathy​on August 1, 2026 at 10:17 am

Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Cristina Manis, Fabrizio Pertusati, James Morewood, Andreas Roos, Felix Kleefeld, Michela Onali, Oksana Pogoryelova, Alexa Derksen, Sally Spendiff, Hanns Lochmuller, Paula Videira, Luigi Atzori, Pierluigi Caboni  

Highly Accurate Sequencing Methods for Low-Frequency Variant Detection

Clin Chem. 2026 Jul 29:hvag074. doi: 10.1093/clinchem/hvag074. Online ahead of print. ABSTRACT BACKGROUND: Next-generation sequencing (NGS), also known as massively parallel sequencing, has become an essential tool across many areas of the life sciences, yet its application to low-frequency variant detection remains constrained by intrinsic error rates and the high cost of ultra-deep sequencing. To … Read more

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