Journal

When rare diseases do not appear as a single entity​Isabel Solareson September 9, 2026 at 10:00 am

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Adv Lab Med. 2026 Jul 16;7(3):234-237. doi: 10.1515/almed-2025-0193. eCollection 2026 Sep. ABSTRACT OBJECTIVES: The coexistence of multisystemic involvement in a young adult raises the need to consider rare metabolic and mitochondrial disorders. We report a case of late-onset propionic acidemia (PPA) that may have contributed to unmasking Leber hereditary optic neuropathy (LHON), an extremely infrequent … Read more

Appearances can be deceptive: acute myeloid leukaemia simulating chronic lymphocytic leukaemia​Beatriz Gómez Horsefieldon September 9, 2026 at 10:00 am

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Adv Lab Med. 2026 May 20;7(3):229-233. doi: 10.1515/almed-2025-0184. eCollection 2026 Sep. ABSTRACT OBJECTIVES: To report a rare case of acute myeloid leukemia (AML) with abnormal chromatin clumping (ACC) in myeloblasts mimicking chronic lymphocytic leukemia (CLL), highlighting the associated diagnostic challenges. CASE PRESENTATION: An 82-year-old woman presented with fatigue, weight loss, and pancytopenia. Peripheral blood film … Read more

Evaluation of LN34 real-time PCR assay for detection of rabies virus in human and animal specimens​Lonika Lodhaon September 9, 2026 at 10:00 am

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Adv Lab Med. 2026 Jul 7;7(3):222-228. doi: 10.1515/almed-2025-0197. eCollection 2026 Sep. ABSTRACT OBJECTIVES: Rabies, a neglected zoonotic encephalitis caused by lyssaviruses, claims around 59,000 lives annually. PCR-based methods are pivotal for laboratory confirmation of rabies in humans and animals. The LN34 pan-lyssavirus real time PCR assay has demonstrated good diagnostic performance in detecting rabies viral … Read more

Reference values for serum proenkephalin A in a pediatric and young adult cohort​​on September 9, 2026 at 11:48 am

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Publication date: December 2026 Source: Clinical Biochemistry, Volume 146 Author(s): Marina Morath, Sven Garbade, Kristina Klingbeil, Philipp Romero, Dominic Lenz, Ulrike Mütze, Stine Christ, Alexander Fichtner, Elena Schnabel-Besson, Georg F. Hoffmann, Christian Nußhag, Claus P. Schmitt, Verena Peters

Impact of point of care testing in time to treatment decision-making in emergency departments: a systematic reviewValentina Pecoraroon September 8, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Sep 9. doi: 10.1515/cclm-2026-0604. Online ahead of print. ABSTRACT The main characteristic of point-of-care testing (PoCT) is to provide rapid test results. It remains uncertain whether faster PoCT results truly improve patient management in the emergency department (ED), and how robust the supporting evidence is. This systematic review aimed to … Read more

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