Publication date: Available online 10 September 2026 Source: Practical Laboratory Medicine Author(s): Raí S. Santiago, Marcia H.C. Nascimento, Jaya M.C. Araújo, Bruno B. Castrillo, Paula Z.M. Dias, Regina E. Albano, Carla C. Nascimento, Paulo R. Filgueiras, Valerio G. Barauna, Lívia C.M. Rodrigues
Clin Chem Lab Med. 2026 Sep 11. doi: 10.1515/cclm-2026-0510. Online ahead of print. ABSTRACT OBJECTIVES: Ceruloplasmin (Cp) and non-ceruloplasmin-bound copper (NCC) are measured when evaluating liver disease and disorders of copper (Cu) metabolism. Cp mass concentration is typically determined by immunoassays that detect both apo- and holoceruloplasmin. In contrast, enzymatic assays measure Cp ferroxidase activity … Read more
Clin Chem Lab Med. 2026 Sep 11. doi: 10.1515/cclm-2026-0319. Online ahead of print. ABSTRACT To ensure reported laboratory results are of adequate quality, it is paramount that the set analytical performance specifications (APS) are tailored to the intended uses of the measurand. For measurands with a pivotal position in the clinical pathway, APS should be … Read more
Clin Chem Lab Med. 2026 Sep 11. doi: 10.1515/cclm-2026-0687. Online ahead of print. ABSTRACT OBJECTIVES: Calculated low-density lipoprotein cholesterol (LDL-C) is widely reported, but formula-dependent estimation differences may alter classification near decision thresholds. We assessed formula-dependent LDL-C classification relative to direct LDL-C in UK Biobank and examined cardiovascular outcomes descriptively. METHODS: We analyzed 397,490 participants … Read more
Clin Chem Lab Med. 2026 Sep 11. doi: 10.1515/cclm-2026-0885. Online ahead of print. ABSTRACT OBJECTIVES: Urinary tract infections (UTIs) are very common in clinical practice. Urine culture remains the cornerstone of UTI diagnosis, but urinalysis screening for bacteriuria can improve workflow. The aim of the study was to screen for significant bacteriuria using Aution Eye … Read more
Clin Chem Lab Med. 2026 Sep 11. doi: 10.1515/cclm-2026-1057. Online ahead of print. ABSTRACT OBJECTIVES: Current guidelines advise calcitonin measurements in washout from fine needle aspiration cytology (FNAC) upon inconclusive cytological examination of medullary thyroid cancer (MTC). (Pre-)analytical validation studies of calcitonin measurements in FNAC washout are however missing. In this study, we examined (pre-)analytical … Read more
Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Shuling Chi, Chaochao Ma, Xiaoqi Li, Xuehui Gao, Lian Hou, Xiuzhi Guo, Yunyun Fei, Ling Qiu
Publication date: December 2026 Source: Clinical Biochemistry, Volume 146 Author(s): Tony Badrick, Jeanette Ju Ting Wu, Rebecca Hui Zhang, Wesley Wong
Adv Lab Med. 2026 May 14;7(3):179-186. doi: 10.1515/almed-2026-0028. eCollection 2026 Sep. ABSTRACT OBJECTIVES: Haemolysis is the leading preanalytical cause of sample rejection in coagulation testing. This study prospectively evaluated the impact of spontaneous haemolysis on routine haemostasis assays by comparing paired haemolysed (H) and non-haemolysed (NH) clinical samples. Additionally, analyser flagging behaviour was characterised using … Read more
Adv Lab Med. 2026 Jul 7;7(3):167-170. doi: 10.1515/almed-2026-0087. eCollection 2026 Sep. NO ABSTRACT PMID:42713577 | PMC:PMC13552802 | DOI:10.1515/almed-2026-0087
