Journal

Spuriously elevated estradiol due to immunoassay interference in the workup of a suspected ovarian tumor: Diagnostic pitfalls and laboratory workflow recommendations​​on June 25, 2026 at 12:26 am

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Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Gelsy Arianna Lupoli, Carmela Polito, Giuseppe Jannuzzi, Mariano Fiorenza, Ada Marino, Lavinia Di Meglio, Domenico Salvatore, Daniela Terracciano

Performance validation and clinical utility of a smartphone-based colorimetric system for differentiating exudative and transudative pleural effusions and ascites via total protein quantification​Dandan Liang, Yonghua Zhao, Yufei Guo, Ziqi Li, Zehua Yang174648Academy of Medical Sciences, Shanxi Medical University, Jinzhong, Shanxi, China2The First Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, China3Department of Laboratory, 74648The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, Chinaon May 13, 2026 at 2:24 am

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Annals of Clinical Biochemistry, Ahead of Print. BackgroundTotal protein (TP) is a key indicator to differentiate between pleural effusion (PE) and ascites as exudate or transudate. Rapid quantification of TP can provide more accurate clinical treatment.ObjectiveThis study developed a smartphone-based …

Tumor-Derived HAVCR1 As a Reliable Fluid Biomarker for the Diagnosis of CNS Lymphoma

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Clin Chem. 2026 May 21:hvag036. doi: 10.1093/clinchem/hvag036. Online ahead of print. ABSTRACT BACKGROUND: The early diagnosis of primary CNS lymphoma (PCNSL) is challenging due to its rapid progression and the lack of reliable noninvasive biomarkers. We aimed to identify robust fluid-based biomarkers for PCNSL, with a focus on primary vitreoretinal lymphoma (PVRL), which is a … Read more

Long-read Oxford Nanopore sequencing enables rapid, cost-effective, and comprehensive TTR genetic testing for hereditary transthyretin amyloidosisGilles Millaton May 19, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 May 20. doi: 10.1515/cclm-2026-0553. Online ahead of print. ABSTRACT OBJECTIVES: Hereditary transthyretin amyloidosis (ATTRv) is a rare autosomal dominant disorder caused by pathogenic variants in the TTR gene, with marked clinical heterogeneity and frequent underdiagnosis. Genetic confirmation is essential for patient management but is traditionally based on Sanger sequencing or … Read more

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