Clinical Chemistry

Determinants of Cardiac Myosin Binding Protein C in the General Population

by

Clin Chem. 2025 Mar 20:hvaf013. doi: 10.1093/clinchem/hvaf013. Online ahead of print. ABSTRACT BACKGROUND: Cardiac myosin binding protein C (cMyC) is a novel, cardiac-specific biomarker with an early release profile after acute ischemic myocardial injury. Whether cMyC reflects chronic myocardial injury and left ventricular remodelling in the general population is unknown. The aims of the study … Read more

Carbamylated Albumin, Heart Failure, and Mortality in Patients Undergoing Coronary Angiography

by

Clin Chem. 2025 Mar 19:hvaf021. doi: 10.1093/clinchem/hvaf021. Online ahead of print. ABSTRACT BACKGROUND: Urea is elevated in chronic kidney disease (CKD) and end-stage renal disease (ESRD), and promotes the carbamylation of proteins, including human albumin, on multiple lysine side chains. Higher proportions of carbamylated albumin (C-Alb) have been associated with increased mortality risk in patients … Read more

Pediatric Vaccine-Induced Antibody Thresholds: Rethinking Pre-Immunosuppression Serologic Testing and Revaccination Implications

by

Clin Chem. 2025 Mar 19:hvaf020. doi: 10.1093/clinchem/hvaf020. Online ahead of print. ABSTRACT BACKGROUND: Immune response to vaccination is assessed when adequate vaccine protection is in question or immunosuppression is imminent through measurement of antibody levels, which wane as time from vaccination increases. The serologic cutoff value for adequate response is based on thresholds derived from … Read more

Direct-to-Consumer Testing: Benefits and Concerns of Commercially Accessed Laboratory Tests

by

Clin Chem. 2025 Feb 18:hvaf004. doi: 10.1093/clinchem/hvaf004. Online ahead of print. ABSTRACT BACKGROUND: Promoting self-empowerment of patients and of healthy persons in contemporary health cultures shifts the imperative for initiating laboratory tests from the healthcare professionals (HCP) to the patients themselves. CONTENT: Laboratory testing requested directly by patients without interaction by HCP is called DTCT … Read more

Laboratory Monitoring in Transgender and Gender-Diverse Individuals

by

Clin Chem. 2025 Mar 3;71(3):358-377. doi: 10.1093/clinchem/hvaf001. ABSTRACT BACKGROUND: Increasing numbers of transgender and gender-diverse individuals are seeking initiation of gender-affirming hormone therapy. This aligns an individual’s physical characteristics with their gender identity and improves psychological outcomes. Physical changes, including changes to muscle mass and body fat redistribution, can alter sex-specific laboratory reference ranges. CONTENT: … Read more

deneme bonusu veren siteler - canlı bahis siteleri - casino siteleri casino siteleri deneme bonusu veren siteler canlı casino siteleri