IFCC primary reference procedure for the measurement of catalytic activity concentrations of enzymes at 37 °C. Part 10: Reference procedure for the measurement of catalytic concentration of pancreatic α-amylase​on October 24, 2025 at 1:10 pm

Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Antje Staaden, Francesca Canalias, Ferruccio Ceriotti, Ilenia Infusino, Marjan Veuger, Friederike Weber, Denis Grote-Koska, International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Scientific Division, Working Group on Pancreatic Enzymes (WG-PE)  

Flow Cytometry in Acute Myeloid Leukemia (AML): A Critical Tool for Accurate Diagnosis, Classification, and Monitoring

Clin Chem. 2025 Oct 23:hvaf111. doi: 10.1093/clinchem/hvaf111. Online ahead of print. ABSTRACT BACKGROUND: Flow cytometry is a crucial diagnostic tool in hematopathology. It supports the identification and follow-up of hematolymphoid neoplasms by providing detailed immunophenotypic data and quantification, and is applicable to various specimen types. CONTENT: Classification and management of acute myeloid leukemia (AML), the … Read more

Establishing reference intervals for venous whole blood micronutrients in the healthy older Chinese population via dried blood spot technology​on October 23, 2025 at 12:19 pm

Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Zehao Wang, Huilian Duan, Xiaocui Cheng, Cheng Cheng, Wen Li, Fei Ma, Ruikun He, Zhongxia Li, Mengtong Yang, Di Wang, Zhenghua Huang, Yongjie Chen, Guowei Huang  

Hemolysis index. Can we uncritically trust manufacturer declarations?Alen Vrtaricon October 23, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Oct 23. doi: 10.1515/cclm-2025-1302. Online ahead of print. ABSTRACT OBJECTIVES: Hemolysis is a common preanalytical interference in clinical biochemistry, affecting up to 3.3 % of routine samples and contributing to approximately 60 % of rejected specimens. It results from the release of intracellular constituents, such as hemoglobin and potassium, into … Read more

ReferenceRangeR: a novel tool designed to facilitate reference interval estimation and verificationGunnar Brandhorston October 22, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Oct 23. doi: 10.1515/cclm-2025-0637. Online ahead of print. ABSTRACT OBJECTIVES: Reference intervals (RIs) are essential for interpreting laboratory test results. It is recommended that each medical laboratory establishes and reviews its own RIs. The use of direct methods is often unfeasible for most laboratories, while indirect methods are a more … Read more

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