Recommendations for the study of monoclonal gammopathies in the clinical laboratory. A consensus of the Spanish society of laboratory medicine and the Spanish society of hematology and hemotherapy. Part III: clinical and analytical recommendations for the study of monoclonal gammopathies by MALDI-TOF mass spectrometryCristina Agullóon November 3, 2025 at 11:00 am

Clin Chem Lab Med. 2025 Nov 4. doi: 10.1515/cclm-2025-1056. Online ahead of print. ABSTRACT Monoclonal gammopathies (MGs) represent a diverse group of plasma cell disorders that range from asymptomatic premalignant conditions to aggressive malignancies such as multiple myeloma (MM). Mass spectrometry (MS) based serum analysis offers a non-invasive, highly sensitive alternative to conventional techniques for … Read more

An isotope dilution-liquid-chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of total and free valproic acid in human serum and plasmaTobias Schierscheron November 3, 2025 at 11:00 am

Clin Chem Lab Med. 2025 Nov 4. doi: 10.1515/cclm-2025-1053. Online ahead of print. ABSTRACT OBJECTIVES: An isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (cRMP) was developed and validated to measure serum and plasma concentrations of the total and free form of valproic acid. METHODS: Quantitative nuclear magnetic resonance spectroscopic methodology was … Read more

Creatinine measurement from finger stick dried blood spots with a routine chemistry analyzer for estimation of GFRJ Corné van Damon November 3, 2025 at 11:00 am

Clin Chem Lab Med. 2025 Nov 3. doi: 10.1515/cclm-2025-0979. Online ahead of print. ABSTRACT OBJECTIVES: Measuring creatinine levels is essential for assessing kidney function. However, traditional venous sampling poses challenges in terms of sample collection, storage, and transportation. Recently, dried blood spot (DBS) analysis has emerged as a potential alternative for measuring creatinine levels, although … Read more

The contribution of IL-10 and IL-6 as potential biomarkers for detecting central nervous system involvement in non-Hodgkin lymphomas​​on November 1, 2025 at 4:21 pm

Publication date: December 2025 Source: Clinical Biochemistry, Volume 140 Author(s): Elisa Buzzatti, Fabiana Esposito, Maria Morello, Vanessa Rossi, Maria Christina Cox, Ombretta Annibali, Enrico Santinelli, Maria Antonietta Irno-Consalvo, Giovangiacinto Paterno, Lucia Cardillo, Massimiliano Postorino, Adriano Venditti, Maria Ilaria Del Principe

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