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Evaluating the research parameters available on the Sysmex® XN-series hematology analyzers as markers of dysplasia in peripheral blood​Vicente Aguaderoon March 31, 2025 at 10:00 am

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Adv Lab Med. 2025 Feb 4;6(1):98-102. doi: 10.1515/almed-2025-0003. eCollection 2025 Mar. ABSTRACT OBJECTIVES: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by peripheral blood cytopenias, cellular dysplasia and risk for progression into acute leukemia. Recent studies reveal that some research parameters available on Sysmex XN-1000® hematology analyzers, including immature platelet fraction (IPF), Neutrophil Granularity Index … Read more

Parameters of glycemic variability in continuous glucose monitoring as predictors of diabetes: a prospective evaluation in a non-diabetic general population​Javier Rodríguez Garcíaon March 31, 2025 at 10:00 am

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Adv Lab Med. 2025 Mar 7;6(1):46-51. doi: 10.1515/almed-2025-0011. eCollection 2025 Mar. ABSTRACT OBJECTIVES: To prospectively examine the ability of some glycemic variability metrics from continuous glucose monitoring (CGM) to predict the development of diabetes in a non-diabetic population. METHODS: A total of 497 non-diabetic patients from the AEGIS study were included. Participants used a CGM … Read more

Consensus instability equations for routine coagulation testsRubén Gómez Riojaon March 29, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 Mar 31. doi: 10.1515/cclm-2025-0117. Online ahead of print. ABSTRACT OBJECTIVES: The stability of plasma samples for basic coagulation tests, prothrombin time (PT) and activated partial thromboplastin time (aPTT), has been widely studied. Recently, the Clinical and Laboratory Standards Institute (CLSI) updated its recommendations, extending the acceptable time frame for aPTT. … Read more

A Meta-Analysis and Systematic Review of Cardiac Troponin I vs T in Community Dwelling Adults: Is Specificity at Risk?

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Clin Chem. 2025 Mar 27:hvaf023. doi: 10.1093/clinchem/hvaf023. Online ahead of print. ABSTRACT BACKGROUND: Cardiac troponin I and T measured by high-sensitivity assays (hs-cTn) are detectable in most ambulatory adults. Hs-cTnI and T may perform differently for prediction of cardiovascular (CV) events. In adults with myopathies and advanced age, hs-cTnT can lose CV specificity. We undertook … Read more

Comparison of three blood collection tubes for 16 biochemical analytes and stability assessment of selected analytes: VACUETTE® CAT serum Sep clot activator tube, VACUETTE® LH lithium heparin Sep tube, and VACUETTE® CAT serum fast separator tube​Jong Do Seo, Yeon Jae Lee, Changhee Ha, Ju Hee Choi, Seon-Hyeon Shin, Hye Young Han, Hyun-Joong Kim, Sung Hea Kim, Bum Sung Kim, Hanah Kim, Hee-Won Moon, Mina Hur, Yeo-Min Yun1Department of Laboratory Medicine, 119754Konkuk University Medical Center, Seoul, Korea2Department of Cardiovascular Medicine, 58933Konkuk University School of Medicine, Seoul, Korea3Department of Laboratory Medicine, 58933Konkuk University School of Medicine, Seoul, Koreaon March 25, 2025 at 9:29 am

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Annals of Clinical Biochemistry, Ahead of Print. BackgroundAnalytical performance of VACUETTE® CAT Serum Fast Separator Tube (SFT; Greiner Bio-One, Austria), recently developed quick-clotting serum separator, was evaluated for correlation and stability, comparing with VACUETTE® CAT Serum Sep Clot …

Placental Biomarker Testing for Evaluation of Suspected Preeclampsia

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Clin Chem. 2025 Mar 25:hvaf024. doi: 10.1093/clinchem/hvaf024. Online ahead of print. ABSTRACT BACKGROUND: Worldwide, hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and neonatal morbidity and mortality (Semin Perinatol 2009;33:130-7). This is especially true in the United States where preeclampsia is a leading cause of premature births (Hypertens Pregnancy 2016;35:510-9 and Lancet … Read more

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