Journal

Comparative analysis of three platforms for serum NfL quantification in healthy controls and MS patientsJustina Dargvainieneon December 17, 2025 at 11:00 am

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Clin Chem Lab Med. 2025 Dec 18. doi: 10.1515/cclm-2025-1476. Online ahead of print. ABSTRACT OBJECTIVES: Neurofilament light chain (NfL) is a biomarker of neuroaxonal damage in various neurological conditions, including multiple sclerosis (MS). With new analytical platforms entering the market, standardization of serum NfL (sNfL) measurement is essential. This study compared sNfL levels across three … Read more

Development and validation of a candidate reference measurement procedure for free triiodothyronine and free thyroxine in human serum using equilibrium dialysis isotope-dilution liquid chromatography-tandem mass spectrometryMin Zhanon December 17, 2025 at 11:00 am

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Clin Chem Lab Med. 2025 Dec 18. doi: 10.1515/cclm-2025-0874. Online ahead of print. ABSTRACT OBJECTIVES: Free triiodothyronine (FT3) and free thyroxine (FT4) are important diagnostic markers for assessing thyroid function. However, their accurate quantification remains challenging due to low serum concentrations. Significant variability exists among current assay methods for measuring FT3 and FT4. This study … Read more

Comparative Evaluation of Two Different Blood Collection Tubes For Hematological and Biochemical Testing​on December 17, 2025 at 3:53 pm

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Publication date: Available online 16 December 2025 Source: Practical Laboratory Medicine Author(s): Michela Salvatici, Francesca Carreras, Monica Gaimarri, Francesca Delia Sansico, Paolo Marinoni, Chiara Masserini, Barbara Bianchi, Carmen Sommese, Lorenzo Drago

Association of Serum Uromodulin and Carbamylated Albumin with All-Cause and Cardiovascular Mortality in Patients with No or Mild Chronic Kidney Disease

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Clin Chem. 2025 Dec 16:hvaf166. doi: 10.1093/clinchem/hvaf166. Online ahead of print. ABSTRACT BACKGROUND: Serum uromodulin (SUmod) and carbamylated albumin (C-Alb) are emerging biomarkers for chronic kidney disease (CKD) progression and mortality. SUmod reflects tubular health, while C-Alb is associated with excretory kidney function, CKD progression, and cardiovascular (CV) mortality. We hypothesized that the combined use … Read more

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