Journal

Moving to practice with the application of Milan model 1b-based analytical performance specificationsMauro Panteghinion September 24, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 Sep 25. doi: 10.1515/cclm-2025-1014. Online ahead of print. ABSTRACT The definition of analytical performance specifications (APS) by the Milan model 1b is based on indirect approaches investigating the impact of analytical performance of the laboratory test on clinical classification and thereby on the probability of patient outcomes. As direct diagnostic … Read more

Does patient-based data monitoring allow us to reconsider the relationship between IQC and EQA?Tony Badrickon September 23, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 Sep 24. doi: 10.1515/cclm-2025-1133. Online ahead of print. ABSTRACT Currently, there is no accepted standard practice for determining the frequency of EQA challenge. The challenge frequency has evolved based on history and local requirements. However, EQA frequency should be based on identifying patient risks caused by poorly performing laboratories, methods, … Read more

Comparative analysis of ISO 15189:2022 with earlier versions with reference to ethicsSudip K Dattaon September 23, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 Sep 24. doi: 10.1515/cclm-2025-0884. Online ahead of print. ABSTRACT OBJECTIVES: The International Organisation for Standardisation (ISO) 15189 standard provides the requirements for quality and competence in medical laboratories. It aims to ensure that laboratories deliver accurate and reliable results for patient care. The first version of the same was published … Read more

EQALM recommendations for the analytical performance specifications for blood smear interpretation in haematology: a need for standardizationStéphanie Albarèdeon September 23, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 Sep 24. doi: 10.1515/cclm-2025-1011. Online ahead of print. ABSTRACT OBJECTIVES: The European Organization for External Quality Assurance Providers in Laboratory Medicine (EQALM) Haematology Working Group (WG) has previously provided two guidelines to support the standardization of haematology blood smear external quality assessment (EQA) (Vives CJL, Albarède S, Flandrin G, Heller … Read more

Evaluation of urine albumin-to-creatinine ratio analysis using strip test as a screening method for urinary albumin determination in primary care​Paula Liébanas Garcíaon September 22, 2025 at 10:00 am

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Adv Lab Med. 2025 May 1;6(3):345-350. doi: 10.1515/almed-2024-0068. eCollection 2025 Sep. ABSTRACT OBJECTIVES: The determination of urinary albumin, crucial for chronic kidney disease (CKD) diagnosis and monitoring, typically employs quantitative techniques as the gold standard. However, semi-quantitative methods such as urine reagent strips show promise as cost-effective and rapid screening tools. This study aims to … Read more

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