Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Fuguo Zhan, Tianbin Chen, Jun Liang, Can Liu, Mingdong Huang, Longguang Jiang
Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Baoming He, Jing Gan, Junjuan Mao, Xiao Wang, Dong Yang, Tong Peng, Jianlin Liu, Xinying Jing, Li Meng, Quekun Peng
Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Yinyi Chen, Kexin Han, Liping Wei, Xinlu Sun, Yanzhao Liu, Qunxia Wang, Yang Wu, Simei Chen, Jianlin Yu, Yi Luo, Lili Wen, Liming Tan
Clin Chem Lab Med. 2026 Jan 12. doi: 10.1515/cclm-2025-1644. Online ahead of print. ABSTRACT BACKGROUND: Method-comparison studies in laboratory medicine are routinely interpreted using regression-based or Bland-Altman analyses. Although useful descriptively, these statistical procedures are frequently misapplied to infer “agreement”, “equivalence”, or “interchangeability”. Such interpretations overlook essential metrological conditions – including the definition of the … Read more
Clin Chem. 2026 Jan 9:hvaf181. doi: 10.1093/clinchem/hvaf181. Online ahead of print. ABSTRACT BACKGROUND: Digital polymerase chain reaction (dPCR) is widely recognized for its high sensitivity in detecting low-frequency variants; however, conventional 2-color systems have limited multiplex capacity. Expanding this capability is essential for simultaneous detection of multiple driver mutations in cancer-related genes. KRAS and GNAS … Read more
Publication date: Available online 8 January 2026 Source: Practical Laboratory Medicine Author(s): Yuki Fujiwara, Yuzuru Takei, Hiroto Nakazawa
Publication date: Available online 8 January 2026 Source: Clinical Biochemistry Author(s): Xiaofang Xuan, Minxia Zhang, Yaqi Fang, Liyun Su, Ke Xu
Clin Chem Lab Med. 2026 Jan 12. doi: 10.1515/cclm-2025-1428. Online ahead of print. ABSTRACT OBJECTIVES: The rapid emergence of highly potent synthetic opioids represents a growing challenge for forensic and clinical laboratories. METHODS: We report the first identification in Europe of methiodone (IC-26) and the first detection in France of cychlorphine in drug samples collected … Read more
Clin Chem Lab Med. 2026 Jan 9. doi: 10.1515/cclm-2025-1222. Online ahead of print. ABSTRACT OBJECTIVES: To establish evidence-based analytical performance specifications (APS), specifically allowable total error (TEa), for five fundamental semen analysis parameters (sperm concentration, progressive motility, total motility, morphology, and vitality) in China utilizing the state-of-the-art model, and to compare these specifications with existing … Read more
Clin Chem Lab Med. 2026 Jan 9. doi: 10.1515/cclm-2025-1101. Online ahead of print. ABSTRACT OBJECTIVES: Evolution is difficult to predict for some patients at emergency department (ED). The soluble urokinase plasminogen activator receptor (suPAR) is a non-specific prognostic inflammatory blood biomarker with a high negative predictive value for pejorative outcomes. The aim of this study … Read more
