Journal

Outlook on ACADSB variants shaping metabolomic patterns and clinical outcomes − experience from a Central European country​​on February 21, 2026 at 5:42 pm

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Publication date: March 2026 Source: Clinical Biochemistry, Volume 142 Author(s): Andrej Bandura, Ján Chandoga, Jerguš Vengríni, Miriama Juhosová, Alžbeta Vavrová, Elena Gregová, Miroslava Lysinová, Zuzana Mydlová, Katarína Brennerová, Jana Šaligová, Danka Maceková, Daniel Böhmer

T-cell receptor beta constant 1 flow cytometry for diagnosing clonality in mature T-cell neoplasms: a systematic review and meta-analysis of diagnostic accuracyPablo Adrian Biaggionion February 19, 2026 at 11:00 am

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Clin Chem Lab Med. 2026 Feb 20. doi: 10.1515/cclm-2025-1376. Online ahead of print. ABSTRACT INTRODUCTION: Accurate assessment of T-cell clonality is key for diagnosing mature T-cell neoplasms. TRBC1-based flow cytometry provides a rapid, robust, and cost-efficient approach. This systematic review and meta-analysis assessed the diagnostic accuracy of TRBC1 flow cytometry (TRBC1-FC) for detecting T-cell clonality … Read more

Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

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Clin Chem. 2026 Feb 19:hvag005. doi: 10.1093/clinchem/hvag005. Online ahead of print. ABSTRACT BACKGROUND: The provision of prenatal genetic screening in 3 core clinical contexts-recessive conditions, aneuploidy, and serological incompatibility-involves multiple tests across reproductive partners. This complexity limits utilization and impairs adherence to guideline-recommended care, particularly in carrier screening, where male partners are frequently not tested … Read more

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