Journal

Serum Biomarkers for the Non-Invasive Assessment of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): An Update

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Clin Chem. 2026 Jul 10:hvag077. doi: 10.1093/clinchem/hvag077. Online ahead of print. ABSTRACT BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease, represents the leading cause of chronic liver disease globally. The increasing prevalence of the metabolic syndrome has driven a parallel rise in MASLD-related morbidity and mortality. Accurate assessment of … Read more

Looking back to look forward: can analytical performance be successfully linked to health outcomes in laboratory medicine?Katy J L Bellon July 10, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0643. Online ahead of print. ABSTRACT The 2015 Milan consensus proposed three models for analytical performance (APS) specifications for laboratory tests. Model 1 recommends defining analytical performance specifications based on impact on clinical outcomes. We undertook a targeted literature review to identify and evaluate studies using indirect … Read more

Clinical validation of an automated extraction protocol and liquid chromatography single quadrupole mass spectrometry (LC-MS) method for plasma vitamins A and E analysisRowan Hellieron July 10, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0108. Online ahead of print. ABSTRACT OBJECTIVES: Quantitation of plasma vitamins A and E is essential for assessing nutritional status. Traditional methods typically involve liquid-liquid extraction followed by high-performance liquid chromatography with UV detection (HPLC-UV). In this study, we evaluated an automated sample extraction-method paired with liquid … Read more

Impact of a computerized intervention to optimize laboratory tests ordering: one-year follow-up in a geriatric unitEdith Rengueton July 10, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0938. Online ahead of print. ABSTRACT OBJECTIVES: Approximately 30 % of laboratory tests are ordered inappropriately, substantially impacting patient care, costs, and carbon footprint of laboratories. Predefined laboratory test panels are a pragmatic and routinely used tool in laboratories, where tests are bundled for efficiency to diagnose … Read more

Laboratory Medicine for SocietyTomáš Zimaon July 9, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Jul 10. doi: 10.1515/cclm-2026-0977. Online ahead of print. ABSTRACT This collective opinion paper, based on presentations delivered during the two-day European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference 2026, “Laboratory Medicine for Society” (Prague, Czech Republic, 24-25 April 2026) offers a forward-looking overview of the Federation’s strategic … Read more

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