Clinical Chemistry

DPYD Sequencing Identifies More Clinically Relevant Variants as Compared to Targeted Genotyping

by

Clin Chem. 2026 Mar 9:hvag007. doi: 10.1093/clinchem/hvag007. Online ahead of print. ABSTRACT BACKGROUND: DPYD testing can identify patients at risk for severe toxicity when a standard fluoropyrimidine antineoplastic dose is prescribed. Sequencing-based methods detect rare variants, which require classification. METHODS: DPYD sequencing results over a 9-year period through to 2024 were analyzed. The dataset was … Read more

Universal Presence of Gene/Variant Nomenclature Errors in Journal Manuscript Submissions

by

Clin Chem. 2026 Mar 7:hvag010. doi: 10.1093/clinchem/hvag010. Online ahead of print. ABSTRACT BACKGROUND: Accurate descriptions of human genomic variants are crucial for gene-disease association, discovery, and clinical diagnosis. Although standardized genomic nomenclature, expertly curated and promulgated by the Human Genome Variation Society and the International Standing Committee on Human Cytogenomic Nomenclature, is strongly encouraged in … Read more

deneme bonusu veren siteler - canlı bahis siteleri - casino siteleri casino siteleri deneme bonusu veren siteler canlı casino siteleri cURL Hatası: OpenSSL SSL_connect: SSL_ERROR_SYSCALL in connection to lkl.dolarkurum.com:443