ccinfoadmin

How to handle lipemic CBC samples on Sysmex hematology analyzers?​Vanja Radišić Biljakon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Mar 20;6(2):166-172. doi: 10.1515/almed-2024-0206. eCollection 2025 Jun. ABSTRACT OBJECTIVES: Lipemia poses a significant preanalytical problem for complete blood count (CBC) measurement due to limited and non-standardized methods for recognition and removal. We aimed to verify the optical hemoglobin (Hb-O) measurements on the Sysmex XN-1000 hematology analyzer (HA) as a possible reliable … Read more

Diagnosis of hemogobinopathies in the clinical laboratory: an occult Hofu hemoglobin on HPLC​Maitane Echeverría Urrozon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Jan 23;6(2):213-216. doi: 10.1515/almed-2024-0175. eCollection 2025 Jun. ABSTRACT OBJECTIVES: Hemoglobinopathies are disorders affecting the structure, function and/or production of hemoglobin. These conditions are caused by mutations in the genes encoding globin synthesis. The highly variable clinical manifestations of hemoglobin disorders range from asymptomatic forms to severe anemia. Laboratory tests are crucial … Read more

Data science applied to the assessment of biological variation estimates​Fernando Marques-Garciaon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Apr 1;6(2):154-159. doi: 10.1515/almed-2025-0042. eCollection 2025 Jun. ABSTRACT INTRODUCTION: Data science is an umbrella term encompassing a set of tools and processes that make it possible to extract new information from structured or unstructured databases. This scientific discipline is gaining relevance in healthcare. In the clinical laboratory, the multiple applications of … Read more

Effect of long-term frozen storage on stability of kappa free light chain indexMartin Schmidaueron May 28, 2025 at 10:00 am

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Clin Chem Lab Med. 2025 May 8. doi: 10.1515/cclm-2025-0125. Online ahead of print. ABSTRACT OBJECTIVES: To investigate whether frozen storage duration influences κ-FLC index. METHODS: CSF and serum samples of patients with multiple sclerosis collected for routine diagnostic purposes had been stored at -20 °C. κ-FLC and albumin concentrations were measured at two different timepoints, … Read more

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