ccinfoadmin – Page 110 – Clinical Chemistry INFO

Determination of the biological variation and reference change value of lipoprotein (a)Kofi Antwi, Paul Downie, Wycliffe MbagayaDepartment of Clinical Biochemistry, 1984University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UKon February 26, 2025 at 3:49 am

March 18, 2025 by ccinfoadmin

Annals of Clinical Biochemistry, Ahead of Print. BackgroundUnderstanding lipoprotein (a) [Lp(a)] measurement variability is essential in establishing its coronary heart disease (CHD) association, and optimizing assessment and management of atherosclerotic cardiovascular disease (ASCVD) risk. We …

Paediatric reference ranges for plasma chromogranin ASofie Lieberoth, Frederik Friis-Hansen, Lennart Friis-Hansen1Department of Clinical Biochemistry, Odense University Hospital, 11286University of Southern Denmark, Odense, Denmark2Department of Clinical Biochemistry, 53166Bispebjerg and Frederiksberg Hospitals, Copenhagen, Denmark3Department of Clinical Research, 11286University of Southern Denmark, Odense, Denmarkon September 15, 2023 at 2:15 am

March 18, 2025 by ccinfoadmin

Annals of Clinical Biochemistry, Ahead of Print. BackgroundNeuroendocrine neoplasms (NENs) are a heterogeneous group of rare diseases with varied aggressiveness originating from endocrine cells belonging to the diffuse endocrine system and most often produce and secrete chromogranin A (CgA). CgA in …

Liquid biopsy in oncology: navigating technical hurdles and future transition for precision medicineMengxiao Xieon March 17, 2025 at 10:00 am

March 18, 2025 by ccinfoadmin

Clin Chem Lab Med. 2025 Mar 19. doi: 10.1515/cclm-2025-0271. Online ahead of print. NO ABSTRACT PMID:40097315 | DOI:10.1515/cclm-2025-0271

Artificial base mismatches-mediated PCR (ABM-PCR) for detecting clinically relevant single-base mutationsCia-Hin Lauon March 15, 2025 at 10:00 am

March 16, 2025 by ccinfoadmin

Clin Chem Lab Med. 2025 Mar 17. doi: 10.1515/cclm-2024-0962. Online ahead of print. ABSTRACT OBJECTIVES: Detecting point mutations with high sensitivity and specificity can be technically very challenging, but it is crucial for early diagnosis and effective drug treatment of cancers. To enable ultrasensitive and ultraspecific detection of single-base mutations in simple and economical ways, … Read more

Impact of biological and genetic features of leukemic cells on the occurrence of “shark fins” in the WPC channel scattergrams of the Sysmex XN hematology analyzers in patients with chronic lymphocytic leukemiaMargot Eggeron March 14, 2025 at 10:00 am

March 14, 2025 by ccinfoadmin

Clin Chem Lab Med. 2025 Mar 17. doi: 10.1515/cclm-2025-0115. Online ahead of print. ABSTRACT OBJECTIVES: In patients with chronic lymphocytic leukemia (CLL), the white progenitor cell (WPC) channel of the Sysmex XN hematology analyzers typically shows a varying proportion of cells in the upper left field of the scattergram, resembling the shape of shark fins. … Read more

Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperatureMaría Sanz-Felision March 13, 2025 at 10:00 am

March 13, 2025 by ccinfoadmin

Clin Chem Lab Med. 2025 Mar 14. doi: 10.1515/cclm-2025-0109. Online ahead of print. ABSTRACT OBJECTIVES: Evaluate the stability of 32 biochemical analytes in venous blood samples stored at 18-25 °C under different time delays prior to centrifugation. METHODS: A prospective study was conducted involving 33 healthy volunteers. Four venous blood samples were collected from each … Read more

The pitfalls and significance of using ratios and calculated parameters in laboratory medicineon March 13, 2025 at 11:44 am

March 13, 2025 by ccinfoadmin

Publication date: Available online 13 March 2025 Source: Clinical Biochemistry Author(s): Loralie J. Langman, Christine LH Snozek, Andre Mattman

Assessment of accuracy, clinical validity, and analytical linearity in point-of-care glucose monitoring devices for diabetes mellitus: A systematic review and meta-analysison March 13, 2025 at 11:44 am

March 13, 2025 by ccinfoadmin

Publication date: Available online 12 March 2025 Source: Clinical Biochemistry Author(s): Michael Pius Ukpe, Anastecia Chinasa Ezeanuka

Sperm recovery from urine in men with retrograde ejaculationErnesto Veiga Álvarezon January 8, 2025 at 11:00 am

March 13, 2025 by ccinfoadmin

Adv Lab Med. 2024 Aug 22;5(4):356-365. doi: 10.1515/almed-2024-0109. eCollection 2024 Dec. ABSTRACT INTRODUCTION: Retrograde ejaculation (RE) consists of the reflux backwards, towards the bladder, of the ejaculate, during the emission phase of ejaculation, causing a total or partial absence of sperm emission, with the consequent diversion of semen into the bladder during the emission phase … Read more

Interference by vitamin B12-macrocomplexes: towards an effective detection and correct interpretation of hypo- and hypervitaminemiaJosé A Delgadoon December 23, 2024 at 11:00 am

March 13, 2025 by ccinfoadmin

Adv Lab Med. 2024 Jul 12;5(4):386-393. doi: 10.1515/almed-2024-0041. eCollection 2024 Dec. ABSTRACT OBJECTIVES: The presence of macro-B12 is a cause of factual hypervitaminemia B12. Precipitation with polyethylene glycol (PEG) is a simple method of removing high-molecular-weight biomolecules. However, “free” molecule may co-precipitate. This fact requires the establishment of reference intervals for the post-precipitation result. The … Read more