An assessment of molecular diagnosis of tuberculosis and multi-drug resistant tuberculosis testing and quality assessment: findings of an international surveyJim F Huggetton September 16, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Sep 5. doi: 10.1515/cclm-2025-0750. Online ahead of print. ABSTRACT Molecular ‘in vitro diagnostic’ (IVD) tests are established for the diagnosis of tuberculosis (TB) and multi-drug resistant TB (MDR-TB). What is less clear is how the use of TB or MDR-TB molecular IVD results differ across regions, whether corroborative tests are … Read more

Not all anti-parietal cell antibody tests are equal for diagnosing pernicious anemiaValentin Lacombeon September 16, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Sep 5. doi: 10.1515/cclm-2025-0671. Online ahead of print. ABSTRACT OBJECTIVES: Pernicious anemia (PA) is a common cause of vitamin B12 deficiency and requires a robust diagnosis to guide lifelong treatment. Anti-parietal cell antibodies (APCA) are frequently used as a diagnostic marker, but their poor specificity raises concerns about overdiagnosis, particularly … Read more

Reliable LC-MS/MS method development and validation for the determination of methylmalonic acid, methylcitric acid, malonic acid, ethylmalonic acid, and total homocysteine in dried blood spots​​on September 14, 2025 at 11:44 am

Publication date: December 2025 Source: Clinical Biochemistry, Volume 140 Author(s): Chunyan Zhang, Nan Bai, Yanling Yang, Yuxuan Cheng, Xiyu He, Meng Wang, Honghui Zhou, Yaping Tian

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