Fecal Microbiota Therapy: Clinical Laboratory Testing and Metabolomic Approaches for Donor Screening, Product Assessment, and Patient Monitoring
Clin Chem. 2025 Dec 19:hvaf156. doi: 10.1093/clinchem/hvaf156. Online ahead of print. ABSTRACT BACKGROUND: The safety and efficacy of fecal microbiota transplantation for prevention of recurrent Clostridioides difficile infection relies on complex interactions between the donor and recipient microbiome. CONTENT: Screening of donor stool has largely aimed to ensure safety; however, metagenomic and metabolic features of … Read more