Journal

Choosing Wisely Canada recommendations for point of care testing utilization in the acute care setting: Expert-based Delphi consensus from the Canadian Society of Clinical Chemists​​on March 3, 2026 at 4:25 pm

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Publication date: March 2026 Source: Clinical Biochemistry, Volume 142 Author(s): Sukhbir Kaur, Saranya Arnoldo, Jennifer Taher, Dana Bailey, Lori Beach, Daniel R. Beriault, Ihssan Bouhtiauy, Miranda Brun, Manal Elnenaei, Yun Huang, Adil I. Khan, David Kinniburgh, Lyne Massicotte, Atoosa Rezvanpour, Karina Rodriguez-Capote, Vinita Thakur, Paul Yip, Allison A. Venner

Diagnostic performance evaluation of the Siemens Healthineers Atellica HEMA 580 hematology analyzer for abnormal cell detection and optimization of immature myeloid cell cut-offsVincenzo De Iuliison March 2, 2026 at 11:00 am

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Clin Chem Lab Med. 2026 Mar 3. doi: 10.1515/cclm-2026-0083. Online ahead of print. ABSTRACT OBJECTIVES: We evaluated the diagnostic performance of the Atellica HEMA 580 hematology analyzer for complete blood count (CBC) parameters compared with the ADVIA 2120i and assessed its capability to flag abnormal cells, and determined optimal cut-offs for immature myeloid cell detection. … Read more

Urinary aldosterone and tetrahydroaldosterone by LC-MS/MS with enzymatic hydrolysis: validation and age-stratified reference intervalsIrene Wijbenga-van der Kooion March 1, 2026 at 11:00 am

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Clin Chem Lab Med. 2026 Mar 2. doi: 10.1515/cclm-2025-1679. Online ahead of print. ABSTRACT OBJECTIVES: Primary aldosteronism (PA) is a common cause of secondary hypertension. To address the specificity limits of immunoassays, we developed and validated an LC-MS/MS method for urinary aldosterone and tetrahydroaldosterone and established method-matched reference intervals for excretion in 24 h urine. … Read more

Machine learning-based integration of antiphospholipid antibodies for predicting pregnancy outcomes in patients with recurrent spontaneous abortion: a multicenter prospective studyXinli Jiangon March 1, 2026 at 11:00 am

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Clin Chem Lab Med. 2026 Mar 2. doi: 10.1515/cclm-2026-0088. Online ahead of print. ABSTRACT OBJECTIVES: Antiphospholipid antibodies (aPLs) are closely associated with recurrent spontaneous abortion (RSA) and adverse pregnancy outcomes (POs). Non-criteria aPLs may aid in diagnosing seronegative aPL-related RSA, but their limited performance often leads to missed or delayed diagnosis. This study aimed to … Read more

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