Clinical Chemistry and Laboratory Medicine

From research to reality: real-world effectiveness of point-of-care testing in the emergency departmentSalomón Martin-Pérezon May 5, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0289. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate the real-world impact of Point-of-Care Testing on care timeliness and patient flow in the emergency department. METHODS: A before-and-after, matched-cohort study was conducted involving 25,291 patients with Emergency Severity Index levels 3-4. A POCT group (n=8,746) was compared … Read more

Capillary dried blood microsampling is not suited for dihydropyrimidine dehydrogenase (DPD) phenotypingKevin Vandenbrouckeon May 5, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0146. Online ahead of print. ABSTRACT OBJECTIVES: Dihydropyrimidine dehydrogenase (DPD) phenotyping through uracil and dihydrouracil determination is a well-established approach to identify (partial) DPD deficiencies prior to fluoropyrimidine chemotherapy. However, preanalytical stability has challenged this test for years. This study therefore investigated whether dried blood spots (DBS) … Read more

Essential laboratory tests in emergencies; on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE)Giuseppe Lippion May 5, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0577. Online ahead of print. ABSTRACT This article aims to define a minimum panel of essential laboratory tests to be used in emergency and disaster settings through expert consensus. A structured survey was distributed to the 24 members of the European Federation of Clinical Chemistry and Laboratory … Read more

Clinical validation and implementation of mSTOP, a machine learning-based, longitudinal prediction model for the early identification of non-small cell lung cancer patients who not benefit from immune checkpoint inhibitor treatmentHuub H van Rossumon April 29, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1624. Online ahead of print. ABSTRACT OBJECTIVES: There has been a lot of interest in the field of laboratory medicine regarding the use of machine learning (ML)-based prediction models. The longitudinal ML-based Serum Tumor marker-based Outcome Prediction (STOP) model was previously developed to identify non-small cell lung … Read more

Reply to “Biological variation of serum cholinesterase activity in healthy subjects”: analytical validation of cholinesterase activity measurement in routine practice: experience from a French clinical laboratoryPierre Mercieron April 29, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0465. Online ahead of print. NO ABSTRACT PMID:42053521 | DOI:10.1515/cclm-2026-0465

No association between high plasma ionized calcium and minor neuropsychological symptoms in two general population cohortsCamilla J Kobyleckion April 29, 2026 at 10:00 am

by

Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1356. Online ahead of print. ABSTRACT OBJECTIVES: Hypercalcemia has been associated with various non-specific minor neuropsychological symptoms but mainly in patient cohorts. Whether hypercalcemia is the cause or an innocent bystander in relation to these symptoms remains unclear. METHODS: We included 5,917 individuals from the Copenhagen City … Read more

deneme bonusu veren siteler - canlı bahis siteleri - casino siteleri casino siteleri deneme bonusu veren siteler canlı casino siteleri error code: 520