Advanced Laboratory Medicine

Utility of PSA in extracellular vesicles as a follow-up biomarker in prostate cancer​Amaia Sandúaon December 30, 2025 at 11:00 am

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Adv Lab Med. 2025 Jul 17;6(4):442-449. doi: 10.1515/almed-2025-0023. eCollection 2025 Dec. ABSTRACT OBJECTIVES: Prostate-specific antigen (PSA) circulates bound to extracelular vesicles (EVs). Levels of this PSA form (ev-PSA) are higher in prostate cancer (PCa) compared to benign pathologies and healthy controls, being the PSA extracellular vesicles/serum (ev/srm) ratio potentially useful as PCa diagnostic biomarker. We … Read more

Design and cost-effectiveness assessment of a model based on point-of-care testing for the improvement of the resolution of hospital emergencies​Marta Jimenez-Barraganon December 30, 2025 at 11:00 am

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Adv Lab Med. 2025 Jul 18;6(4):458-466. doi: 10.1515/almed-2024-0210. eCollection 2025 Dec. ABSTRACT OBJECTIVES: Emergency department (ED) crowding is a quality of care and financial problem. Among its causes are long length of stay in the ED (ED LoS). One of identified causes is prolonged Turnaround Time (TAT) for complementary tests, including laboratory tests. The main … Read more

Comparison of four different analyzers for prenatal trisomy 21 risk​Natalia García-Simónon December 30, 2025 at 11:00 am

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Adv Lab Med. 2025 Jun 4;6(4):411-418. doi: 10.1515/almed-2025-0008. eCollection 2025 Dec. ABSTRACT OBJECTIVES: Various analyzers are available for measuring first-trimester combined screening for trisomy 21 (T21) serum biomarkers (free-beta subunit of the human chorionic gonadotropin (β-hCG) and the pregnancy-associated plasma protein A (PAPP-A)). Our aim is to compare the analytical performance of four different analyzers … Read more

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