Adv Lab Med. 2025 Sep 1;7(1):10-15. doi: 10.1515/almed-2025-0121. eCollection 2026 Mar. ABSTRACT For centuries, the only ‘semeiological and laboratory’ test that the physician had at his disposal to point towards to a diagnosis was the urine test. It was based on the chemical and physical properties evaluation of the sample. During the last decade of … Read more
Adv Lab Med. 2025 Dec 8;7(1):52-58. doi: 10.1515/almed-2025-0087. eCollection 2026 Mar. ABSTRACT OBJECTIVES: To evaluate the feasibility of urinary DNA as a noninvasive alternative for high-resolution HLA genotyping and validate its concordance with conventional blood-based methods. METHODS: Matched urine and blood samples were collected from 11 healthy volunteers. Urinary DNA was extracted using an optimized … Read more
Adv Lab Med. 2025 Nov 24;7(1):59-63. doi: 10.1515/almed-2025-0133. eCollection 2026 Mar. ABSTRACT OBJECTIVES: To evaluate the analytical performance of platelet counts obtained by impedance- and optical-based methods on the DxH-900 and BC-6800 Plus analyzers, and by digital morphology using the CellaVision DM9600, in comparison with the international reference method (IRM), in samples with thrombocytopenia and … Read more
Adv Lab Med. 2025 Oct 3;7(1):68-73. doi: 10.1515/almed-2025-0107. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Primary cardiac lymphoma represents an extremely rare entity of extranodal non-Hodgkin lymphoma. CASE PRESENTATION: We report the case of a woman who presented with dyspnea, asthenia, chest pain, cough, and odynophagia. Investigations revealed a diffuse large B-cell lymphomas type primary cardiac lymphoma … Read more
Adv Lab Med. 2026 Jan 15;7(1):43-51. doi: 10.1515/almed-2025-0144. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Alpha-fetoprotein L3 (AFP-L3 %) and protein induced by vitamin K absence-II (PIVKA-II) are used in diagnostic scores such as GAAD, GALAD, and ASAP for hepatocellular carcinoma (HCC) detection. Advanced liver fibrosis (ALF) is diagnosable by the liver fibrosis index and could be … Read more
Adv Lab Med. 2025 Oct 29;7(1):78-79. doi: 10.1515/almed-2025-0157. eCollection 2026 Mar. NO ABSTRACT PMID:41853787 | PMC:PMC12994700 | DOI:10.1515/almed-2025-0157
Adv Lab Med. 2026 Feb 9;7(1):34-42. doi: 10.1515/almed-2025-0088. eCollection 2026 Mar. ABSTRACT OBJECTIVES: The establishment of reference intervals (RIs) for biochemical parameters is crucial for the accurate interpretation of laboratory test results and clinical decision-making. This study aims to evaluate the feasibility of determining RIs using an indirect approach, which analyzes routine clinical samples instead … Read more
Adv Lab Med. 2025 Dec 5;7(1):26-33. doi: 10.1515/almed-2025-0179. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Arterial blood gas (ABG) analysis is vital in emergency care setting for assessing respiratory and metabolic status, but its reliability is highly jeopardized by pre-analytical errors, which constitute up to 70 % of laboratory errors. This study evaluated pre-analytical quality indicators (QIs) … Read more
Adv Lab Med. 2025 Sep 3;7(1):64-67. doi: 10.1515/almed-2025-0070. eCollection 2026 Mar. ABSTRACT OBJECTIVES: Urinary acidification plays a crucial role in acid-base homeostasis, its evaluation being necessary in the differential diagnosis of metabolic acidosis. The practical limitations of the functional tests required to confirm an acidification disorder point out the need for a simple screening method … Read more
Adv Lab Med. 2025 Sep 5;7(1):1-9. doi: 10.1515/almed-2025-0118. eCollection 2026 Mar. ABSTRACT INTRODUCTION: Adverse drug reactions (ADRs) represent a major public health problem. A significant subset of these reactions, particularly delayed-type hypersensitivity reactions and severe cutaneous adverse reactions (SCARs), show a strong association with specific alleles of the human major histocompatibility complex (HLA). The following … Read more
