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Plasma Neprilysin in Heart Failure: Response Dynamics and Clinical Associations Are Immunoassay Dependent

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Clin Chem. 2025 May 21:hvaf056. doi: 10.1093/clinchem/hvaf056. Online ahead of print. ABSTRACT BACKGROUND: Discordance among published findings on the plasma concentrations, response dynamics, and clinical associations of plasma neprilysin (NEP) in health and heart failure (HF) require clarification. METHOD: Using a newly developed glycosylation-sensitive monoclonal antibody sandwich ELISA (NEPCVRI), plasma NEP was measured in 99 … Read more

Improving Transfusion Practices for Pediatric Patients​on May 9, 2025 at 4:00 am

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Yale Laboratory Medicine faculty, including Drs. Jeanne Hendrickson, George Hauser, Thomas Binns and Nalan Yurtsever, attended the Domestic Steering Committee meeting for REDS-IV-P held April 29th-May 1st in Bethesda, MD. Yale is one of four hubs involved in REDS, a multisite project aiming to improve transfusion practices in the pediatric population. REDS-IV-P stands for Recipient … Read more

The frequency of JAK2 V617F mutation and its association with low EPO levels in polycythemia vera patients​Recai Aci Adem Keskin Özlem Sezer Taner Karakaya Samet Semiz Halit Kızılet a Söke Vocational School of Health Services, Aydın Adnan Menderes University, Aydın, Turkeyb Department of Medical Biochemistry, Faculty of Medicine, Aydın Adnan Menderes University, Aydın, Turkeyc Department of Internal Medicine, Department of Medical Genetics, Samsun University Faculty of Medicine, Samsun, Turkeyd Department of Medical Biology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkeyon May 8, 2025 at 9:37 am

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Converting waste into value. Stability of leftover EDTA whole blood: serum vs. plasma for nine clinical chemistry analyses​Cindhya Sithiravel Tor A. Strand Ingunn Tjelde Fauskrud Ine Kathrine Granberg Hege K. Tjølsen Hermansen Ragnhild Røysland Kjersti S. Bakken a Multidisciplinary Laboratory Medicine and Medical Biochemistry, Akershus University Hospital, Lørenskog, Norwayb Department of Research, Innlandet Hospital Trust, Lillehammer, Norwayc Center for International Health, University of Bergen, Bergen, Norwayd Department of Microbiology, Innlandet Hospital Trust, Lillehammer, Norwaye Institute of Clinical Medicine, University of Oslo, Oslo, Norwayf Women’s Clinic, Innlandet Hospital Trust, Lillehammer, Norwayon April 20, 2025 at 6:22 am

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Volume 85, Issue 3, MAY 2025, Page 214-219.

Stability of 17 endocrine analytes in serum or plasma after four cycles of repeated freezing and thawing​Elisabet Tjernvoll Arne Åsberg Ingrid Alsos Lian Lena Løfblad Gunhild Garmo Hov Ketil Thorstensen Gustav Mikkelsen a Department of Clinical Chemistry, Trondheim University Hospital, Trondheim, Norwayb Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norwayon April 17, 2025 at 12:34 pm

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Volume 85, Issue 3, MAY 2025, Page 190-195.

Evaluation of hemolysis as a source of interference in the determination of S-100B using the LIAISON® S100 assay​Jaime I. Sainz de Medrano Judit Julian Irene Martínez Anna Escalante Helena Castellà Victoria Ortiz Esther Fernández-Galán Javier Laguna a Department of Biochemistry and Molecular Genetics, CDB, Hospital Clínic, Barcelona, Spainb CORE Laboratory, CDB, Hospital Clínic, Barcelona, Spainc Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spainon April 11, 2025 at 6:36 am

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Volume 85, Issue 3, MAY 2025, Page 220-222.

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