ccinfoadmin Clin Chem Lab Med. 2026 Aug 24. doi: 10.1515/cclm-2026-1335. Online ahead of print. NO ABSTRACT PMID:42631445 | DOI:10.1515/cclm-2026-1335
Clin Chem Lab Med. 2026 Aug 24. doi: 10.1515/cclm-2026-1125. Online ahead of print. ABSTRACT Hospital-acquired anemia is highly prevalent and largely preventable complication of hospitalization, affecting up to 40-74 % of patients and up to 90 % of intensive care units patients. Excessive diagnostic blood loss from routine phlebotomy represents a significant and modifiable contributor, … Read more
Clin Chem. 2026 Aug 21:hvag105. doi: 10.1093/clinchem/hvag105. Online ahead of print. ABSTRACT BACKGROUND: Plasma proinsulin concentrations are used to investigate hypoglycemia. They have also been proposed as a marker of β-cell function, particularly as a ratio with C-peptide. Immunoassays remain the primary method for measuring proinsulin despite potential limitations. Mass spectrometry-based assays have been described, … Read more
Clin Chem. 2026 Aug 21:hvag100. doi: 10.1093/clinchem/hvag100. Online ahead of print. ABSTRACT BACKGROUND: Multiplexed assays, which simultaneously measure many analytes from a single sample, have become increasingly significant for laboratory diagnosis. Many multiplexed assays with application to clinical diagnosis consist of analyte measurements that can fail individually. In these cases, traditional statistical quantitative quality control … Read more
Clin Chem Lab Med. 2026 Aug 21. doi: 10.1515/cclm-2026-0944. Online ahead of print. ABSTRACT OBJECTIVES: Serum neurofilament light chain (sNfL) reflects neuroaxonal injury in relapsing-remitting multiple sclerosis (RRMS), but its clinical utility is limited by high interindividual variability and confounders such as renal function. Population-based thresholds may therefore be suboptimal for longitudinal monitoring. The reference … Read more
Clin Chem Lab Med. 2026 Aug 21. doi: 10.1515/cclm-2026-0783. Online ahead of print. ABSTRACT OBJECTIVES: Thalassemia and hemoglobinopathies are significant genetic disorders in Thailand. Routine diagnostic methods including complete blood count (CBC), hemoglobin (Hb) analysis, and targeted PCR, are effective for detecting common mutations but limited sensitivity for rare and unstable variants, and complex genotypes. … Read more
Clin Chem. 2026 Aug 20:hvag106. doi: 10.1093/clinchem/hvag106. Online ahead of print. NO ABSTRACT PMID:42621683 | DOI:10.1093/clinchem/hvag106
Clin Chem. 2026 Aug 20:hvag098. doi: 10.1093/clinchem/hvag098. Online ahead of print. ABSTRACT BACKGROUND: We determined whether circulating cardiac troponin I-cardiac troponin T-troponin C (ITC) complex containing long-form cardiac troponin T (long-T ITC) complex and ratios of high-sensitivity cardiac troponin I (hs-cTnI) and high-sensitivity cardiac troponin T (hs-cTnT) could differentiate myocardial infarction (MI) from chronic and … Read more
Clin Chem Lab Med. 2026 Aug 21. doi: 10.1515/cclm-2026-0870. Online ahead of print. ABSTRACT OBJECTIVES: Antiphospholipid antibodies (aPL) are essential biomarkers for classification, diagnosis, and risk stratification of antiphospholipid syndrome (APS). Although automated analytical platforms, such as chemiluminescent immunoassay (CLIA), and particle-based multi-analyte technology (PMAT), are increasingly implemented in routine laboratories, uncertainty remains regarding their … Read more
Clin Chem Lab Med. 2026 Aug 20. doi: 10.1515/cclm-2026-0877. Online ahead of print. NO ABSTRACT PMID:42618552 | DOI:10.1515/cclm-2026-0877
