Commentary on Supratherapeutic Carbamazepine Concentration Following a Recent SARS-CoV-2 Infection
Clin Chem. 2025 Oct 3;71(10):1023. doi: 10.1093/clinchem/hvaf091. NO ABSTRACT PMID:41038609 | DOI:10.1093/clinchem/hvaf091
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Multicenter clinical validation of a novel rapid single-integrated TAT immunoassay and combined thrombosis biomarker panel for venous thromboembolism risk stratification in colorectal canceron October 2, 2025 at 12:45 pm
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Meng Liu, Chaolin Guo, Hongsheng Zhou, Ziyan Xie, Yankun Yang, Kuiqi Jin, Jianqi Nie, Jinhua Xiao, Yang Sun, Zhonghu Bai
Serum neuron-specific enolase – reference interval in Danish children and the impact of preanalytical factorsJacob Rudjord Therkildsenon October 2, 2025 at 10:00 am
Clin Chem Lab Med. 2025 Oct 3. doi: 10.1515/cclm-2025-0582. Online ahead of print. ABSTRACT OBJECTIVES: Neuron-specific enolase (NSE) is a clinically relevant biomarker used in the assessment of neuronal damage and in the diagnosis and monitoring of certain cancers. Despite its diagnostic importance, paediatric-specific reference intervals (RIs) for NSE are currently lacking. This study aimed … Read more
Post-analytical practices in clinical mass spectrometry laboratories: an international survey across 57 countriesJenny Yeuk-Ki Chengon October 1, 2025 at 10:00 am
Clin Chem Lab Med. 2025 Oct 2. doi: 10.1515/cclm-2025-1136. Online ahead of print. ABSTRACT OBJECTIVES: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is increasingly used in clinical laboratories due to its high analytical specificity and multiplexing capabilities. While the pre-analytical and analytical phases have seen significant advances in automation, the post-analytical phase remains a bottleneck with limited … Read more
Serum N-glycans as independent predictors of the incidence of type 2 diabetes: a prospective investigation in the AEGIS cohortIago Carballoon September 30, 2025 at 10:00 am
Clin Chem Lab Med. 2025 Jun 24;63(11):2330-2340. doi: 10.1515/cclm-2025-0045. Print 2025 Oct 27. ABSTRACT OBJECTIVES: Glycosylation is a tightly controlled co-translational and post-translational enzymatic modification. Total N-glycome profiling in blood serum/plasma provides information on the most common serum/plasma glycosylation. Total plasma N-glycome from various population samples displayed predictive ability for type 2 diabetes incidence in … Read more
Diagnostic value of combined coagulation and inflammatory biomarkers in sepsison September 30, 2025 at 3:43 pm
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Guo-Ming Zhang
Expert opinion within the context of the targeted evaluation of Regulation (EU) 2017/746 on in vitro diagnostic medical devices pursuant to Article 111 and Regulation (EU) 2024/1860Michael Vogeseron September 30, 2025 at 10:00 am
Clin Chem Lab Med. 2025 Oct 1. doi: 10.1515/cclm-2025-0941. Online ahead of print. ABSTRACT EU laws are usually evaluated after 10 years; in the case of the IVDR, the targeted evaluation was brought forward and stakeholders in laboratory diagnostics were invited to comment. The Association of the Scientific Medical Societies in Germany (AWMF; Arbeitsgemeinschaft der … Read more
Analysis of urine cell-free DNA copy number and fragment size from healthy individualson September 29, 2025 at 7:57 pm
Publication date: 15 January 2026 Source: Clinica Chimica Acta, Volume 579 Author(s): Jufen Wang, Zilong Wu, Bingyu Wu, Xinghao Lin, Wenhe Wu, Jun Li
Requiem for the Passing-Bablok nonparametric regression in assessing the agreement between two measurement methodsBruno Mario Cesanaon September 28, 2025 at 10:00 am
Clin Chem Lab Med. 2025 Sep 29. doi: 10.1515/cclm-2025-0581. Online ahead of print. ABSTRACT OBJECTIVES: Regulatory guidelines recommend non-parametric Passing-Bablok regression for evaluating the agreement between two measurement methods in laboratory settings. However, concluding for the agreement if the 95 % CI of the slope and of the intercept include 1 and 0, respectively is … Read more
Calculated small-dense and large-buoyant low-density lipoprotein-cholesterol and their ratio in predicting coronary artery disease risk: A cohort study in Thailandon September 27, 2025 at 7:45 pm
Publication date: December 2025 Source: Clinical Biochemistry, Volume 140 Author(s): Thanyatorn Chantivas, Prin Vathesatogkit, Anchalee Chittamma, Nisakron Thongmung, Martin H Kroll, Pornpen Srisawasdi