Use of indirect methods and machine learning algorithms for the estimation of reference intervals, taking cortisol measurements as an exampleFatma Demet Arslanon October 21, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Oct 23. doi: 10.1515/cclm-2025-0984. Online ahead of print. ABSTRACT OBJECTIVES: This study aims to determine reliable reference intervals (RIs) for total cortisol (TC) in adults considering the effects of both age and blood collection time, using indirect methods and machine learning approaches. METHODS: Serum TC results from blood samples collected … Read more

Dental amalgams and blood mercury concentrations in American adultsDavid A Geieron October 19, 2025 at 10:00 am

Clin Chem Lab Med. 2025 Oct 20. doi: 10.1515/cclm-2025-0909. Online ahead of print. ABSTRACT OBJECTIVES: Dental amalgam (50 % mercury (Hg) by weight) is a commonly used material to restore a tooth damaged by decay. In recent years, amalgam safety has become a matter of ongoing controversy. This hypothesis-testing epidemiological study evaluated the relationship between … Read more

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