From venipuncture to self-sampling dried blood spots: a shift in monitoring testosterone levelsAnouk Olthofon January 3, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 5. doi: 10.1515/cclm-2025-1287. Online ahead of print. ABSTRACT OBJECTIVES: Dried blood spot (DBS) sampling enables convenient at-home blood collection, suitable for patients needing regular check-ups, such as those receiving testosterone replacement therapy (TRT). This study assessed the feasibility and reliability of DBS sampling for monitoring testosterone concentrations in patients … Read more

Validation study of the Helena V8 UltraCE capillary elecrophoresis analyserJoris R Delangheon January 2, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 5. doi: 10.1515/cclm-2025-1523. Online ahead of print. ABSTRACT OBJECTIVES: Serum protein electrophoresis is one of the keystone investigations for screening for monoclonal proteins and assessing the serum protein profile. The newly released Helena V8ultra capillary electrophoresis system has been evaluated. METHODS: In total, 164 serum samples were assessed on … Read more

Laboratory findings in patients treated with complement factor C3 inhibitor pegcetacoplanSaskia M C Langemeijeron January 2, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 5. doi: 10.1515/cclm-2025-1270. Online ahead of print. ABSTRACT OBJECTIVES: Complement inhibitor pegcetacoplan binds to C3 and its activation product C3b. Pegcetacoplan has been approved for the treatment of paroxysmal nocturnal hemoglobinuria. Because pegcetacoplan exerts broad inhibition of the complement cascade its efficacy is also investigated in numerous other diseases … Read more

At-home blood collection for clinical chemistry analyses in a kidney transplant population: a feasibility studyJorrit Hoekstraon January 2, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 5. doi: 10.1515/cclm-2025-1199. Online ahead of print. ABSTRACT OBJECTIVES: To investigate the feasibility of at-home collection of liquid capillary blood samples for clinical chemistry analyses. METHODS: Kidney transplant recipients performed a fingerprick to collect capillary blood samples. Samples were kept at room temperature for 24 h before further processing. … Read more

Analytical and diagnostic evaluation of the Anvajo fluidlab 2 analyzer: a novel urine particle analyzer for clinical application using digital holographic microscopy?Sigrid Deprezon January 2, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 2. doi: 10.1515/cclm-2025-1202. Online ahead of print. ABSTRACT OBJECTIVES: The performance of a novel urine particle analyzer, fluidlab 2 (Anvajo GmbH, Dresden, Germany), was evaluated against phase-contrast visual microscopy according to the most recent EFLM European Urinalysis Guideline. METHODS: The fluidlab 2 device combines digital holographic microscopy with neural … Read more

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