Hemoglobin Chapel Hill masquerading as hemoglobin S in newborn sickle cell screening: A case study​​on January 19, 2026 at 3:02 pm

Publication date: Available online 18 January 2026 Source: Clinical Biochemistry Author(s): Natalia Volodko, Michelle L. Parker, Ross Ridsdale, Lauren MacNeil, Iveta Sosova, Mathew P. Estey, Dustin Proctor, Lily Olayinka, Ashley Newbigging, Pierre Bordeleau, Maggie Powell, Victoria Higgins

Analytical Performance Comparison of Three Quantitative Hepatitis B Surface Antigen Assays

Clin Chem. 2026 Jan 16:hvaf191. doi: 10.1093/clinchem/hvaf191. Online ahead of print. ABSTRACT BACKGROUND: Quantitative hepatitis B surface antigen (qHBsAg) assays are important tools for monitoring hepatitis B virus (HBV) infection and treatment response and constitute the primary endpoint in most HBV antiviral trials. To date, no qHBsAg assay has been authorized by the FDA for … Read more

Assessment for potential bias in multiplexed IL-10 and TNF-α from plex countWade M Sanderson January 16, 2026 at 11:00 am

Clin Chem Lab Med. 2026 Jan 19. doi: 10.1515/cclm-2025-0458. Online ahead of print. ABSTRACT OBJECTIVES: Multiplex arrays offer a high-throughput, cost-effective means for quantifying multiple analytes simultaneously, essential for large-scale biomarker research. However, the shared reactive environment in multiplex assays could lead to variations in results compared to single plex assays, potentially impacting outcomes. This … Read more

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