ccinfoadmin Clin Chem Lab Med. 2025 Apr 28. doi: 10.1515/cclm-2025-0402. Online ahead of print. NO ABSTRACT PMID:40277334 | DOI:10.1515/cclm-2025-0402
Clin Chem Lab Med. 2025 Apr 28. doi: 10.1515/cclm-2025-0483. Online ahead of print. NO ABSTRACT PMID:40277300 | DOI:10.1515/cclm-2025-0483
Clin Chem Lab Med. 2024 Dec 31;63(6):1139-1152. doi: 10.1515/cclm-2024-1350. Print 2025 May 26. ABSTRACT OBJECTIVES: Measurements of acid-base status are performed quickly after blood sampling avoiding errors. This necessitates rapid sample transport which can be problematic. This study measures blood sampled in critically ill patients over 180 min and proposes a mathematical physio-chemical model to … Read more
Clin Chem Lab Med. 2025 Apr 25. doi: 10.1515/cclm-2025-0098. Online ahead of print. ABSTRACT OBJECTIVES: Potential coeliac disease (PCD) is defined by the presence of positive CD-specific autoantibodies with a normal/extremely mildly damaged intestinal mucosa. This study sought to examine the progression of PCD in children maintaining a gluten-containing diet and to identify risk factors … Read more
Clin Chem. 2025 Apr 24:hvaf044. doi: 10.1093/clinchem/hvaf044. Online ahead of print. ABSTRACT BACKGROUND: Metagenomic cell-free DNA (cfDNA) sequencing provides a new avenue for diagnosing infectious diseases. Owing to the low concentration and highly fragmented nature of microbial cfDNA in plasma, coupled with methodological complexity, ensuring accurate and comparable metagenomic cfDNA sequencing results has proved challenging. … Read more
Clin Chem. 2025 Apr 24:hvaf043. doi: 10.1093/clinchem/hvaf043. Online ahead of print. ABSTRACT BACKGROUND: In 2009, the Minimum Information for Publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines established standards for the design, execution, and reporting of quantitative PCR (qPCR) in research. The expansion of qPCR into numerous new domains has driven the development of new … Read more
Clin Chem. 2025 Apr 24:hvaf046. doi: 10.1093/clinchem/hvaf046. Online ahead of print. NO ABSTRACT PMID:40272410 | DOI:10.1093/clinchem/hvaf046
Clin Chem Lab Med. 2025 Apr 24. doi: 10.1515/cclm-2025-0329. Online ahead of print. ABSTRACT OBJECTIVES: To explore the reasons behind the lack of commutability in protein solution reference materials (RMs) and seeks to eliminate these factors in order to develop commutable reference materials, using human insulin (hINS) as example, to meet the growing demand for … Read more
Clin Chem Lab Med. 2025 Apr 24. doi: 10.1515/cclm-2025-0240. Online ahead of print. ABSTRACT OBJECTIVES: Serum cholinesterase (ChE) 3.1.1.8 is measured to assess exposure to organophosphorus pesticides and determine deficiency related to prolonged apnea after the induction of anesthesia with certain drugs and less often as an indicator of liver function. Biological variation (BV) is … Read more
Clin Chem Lab Med. 2025 Apr 24. doi: 10.1515/cclm-2025-0478. Online ahead of print. ABSTRACT The negative impact of preanalytical errors on the quality of laboratory testing is now universally recognized. Nonetheless, recent technological advancements and organizational transformations in healthcare – catalyzed by the still ongoing coronavirus disease 2019 (COVID-19 pandemic) – have introduced new challenges … Read more
