The laboratory K-curve: bridging diagnostic innovation and adoptionDamien Grusonon June 26, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 29. doi: 10.1515/cclm-2026-0958. Online ahead of print. NO ABSTRACT PMID:42360908 | DOI:10.1515/cclm-2026-0958
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The contribution of Laboratory Medicine to Precision NeurologyLorenzo Gaetanion June 26, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 26. doi: 10.1515/cclm-2026-0891. Online ahead of print. NO ABSTRACT PMID:42359687 | DOI:10.1515/cclm-2026-0891
Patterns of One-Year Change in HbA1c and Continuous Glucose Monitoring (CGM) Metrics in Older Adults with Type 2 Diabetes
Clin Chem. 2026 Jun 25:hvag067. doi: 10.1093/clinchem/hvag067. Online ahead of print. ABSTRACT BACKGROUND: How changes in hemoglobin A1c (HbA1c) and continuous glucose monitoring (CGM) metrics track together over time is poorly understood, particularly in type 2 diabetes. We investigated the patterns of change in HbA1c and CGM metrics among older adults with type 2 diabetes. … Read more
The effect of Sebia’s CZE IFCC-converted results on carbohydrate-deficient transferrin (CDT) interpretation in driver’s license assessmentsNathan Debunneon June 25, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 26. doi: 10.1515/cclm-2026-0346. Online ahead of print. ABSTRACT OBJECTIVES: Carbohydrate-deficient transferrin (CDT) is a specific biomarker for chronic excessive alcohol consumption. The IFCC Working Group on CDT Standardization recommends 2-sialo-transferrin (2-sialo-Tf) as the sole measurand, with a decision threshold of 2.0 % CDTIFCC using HPLC. This study evaluates the … Read more
Performance of the European Kidney Function Consortium (EKFC) creatinine-based eGFR equation and other eGFR equations in a north European population. A multicentre study in NorwayMaria Averinaon June 25, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 26. doi: 10.1515/cclm-2026-0464. Online ahead of print. ABSTRACT OBJECTIVES: Accurate estimation of glomerular filtration rate (eGFR) is necessary for early detection and staging of chronic kidney disease (CKD), risk stratification, and guiding therapies that prevent complications and progression to advanced CKD. This study aimed to evaluate the performance of … Read more
New insights in primary aldosteronism diagnosis: a prospective multicenter studyKaijuan Wangon June 25, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 26. doi: 10.1515/cclm-2026-0579. Online ahead of print. ABSTRACT OBJECTIVES: The high variability in screening and confirmatory cut-off values for primary aldosteronism (PA) largely reflects the insufficient standardization of current analytical methods. Competitive and sandwich immunoassays show variable correlation with the reference liquid chromatography-tandem mass spectrometry (LC-MS/MS) technique. This prospective … Read more
Editor’s Note: Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer
Clin Chem. 2026 Jun 22:hvag058. doi: 10.1093/clinchem/hvag058. Online ahead of print. NO ABSTRACT PMID:42329672 | DOI:10.1093/clinchem/hvag058
In Reply to Reflexing NT-proBNP for sFlt-1/PlGF Ratios That Fall into the Measurement Uncertainty for Preeclampsia Risk Classification
Clin Chem. 2026 Jun 20:hvag071. doi: 10.1093/clinchem/hvag071. Online ahead of print. NO ABSTRACT PMID:42322433 | DOI:10.1093/clinchem/hvag071
Reflexing NT-proBNP for sFlt-1/PlGF Ratios That Fall into the Measurement Uncertainty for Preeclampsia Risk Classification
Clin Chem. 2026 Jun 20:hvag070. doi: 10.1093/clinchem/hvag070. Online ahead of print. NO ABSTRACT PMID:42322408 | DOI:10.1093/clinchem/hvag070
ProGRP dynamics as a prognostic predictor in advanced medullary thyroid carcinomaAlfredo Campennion June 24, 2026 at 10:00 am
Clin Chem Lab Med. 2026 Jun 25. doi: 10.1515/cclm-2026-0757. Online ahead of print. ABSTRACT OBJECTIVES: Advanced medullary thyroid carcinoma (MTC) is commonly monitored using calcitonin (CT) and carcinoembryonic antigen (CEA) kinetics. Pro-gastrin-releasing peptide (ProGRP) and carbohydrate antigen 19-9 (CA 19.9) have emerged as potential complementary markers, but their longitudinal prognostic value remains unclear. METHODS: This … Read more