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APOB to Estimated APOB Ratio for Screening for the APOE2 Genotype

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Clin Chem. 2026 Aug 3:hvag094. doi: 10.1093/clinchem/hvag094. Online ahead of print. ABSTRACT BACKGROUND: Familial dysbetalipoproteinemia (FDB) is a genetic lipoprotein disorder that can develop in patients homozygous for the apolipoprotein 2 (APOE2) genotype (APOE ɛ2/ɛ2). It is associated with decreased clearance of remnant lipoproteins and increased atherosclerotic cardiovascular disease (ASCVD) risk disproportionate to low-density lipoprotein-cholesterol … Read more

Mapping pediatric cardiac troponin testing worldwide: results from the IFCC survey on emerging applications, standardization needs and accessCatherine L Omosuleon August 3, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Aug 4. doi: 10.1515/cclm-2026-0711. Online ahead of print. ABSTRACT OBJECTIVES: Limited guidance on the use and interpretation of cardiac troponin (cTn) testing in pediatric populations has restricted its broader adoption, despite the significant burden of congenital and acquired cardiac conditions in children. This survey aimed to evaluate global availability, utilization … Read more

Continuous reference curves for hematology and biochemistry analytes in pregnancy – a prospective studyVesna Šupak-Smolčićon August 1, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Aug 3. doi: 10.1515/cclm-2026-0609. Online ahead of print. ABSTRACT OBJECTIVES: Pregnancy involves dynamic metabolic changes that cannot be accurately interpreted using population reference intervals (RI). The aim was to develop continuous reference curves for common hematology and biochemistry laboratory analytes in pregnancy and to assess their agreement with the RIs … Read more

Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathy​on August 1, 2026 at 10:17 am

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Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Cristina Manis, Fabrizio Pertusati, James Morewood, Andreas Roos, Felix Kleefeld, Michela Onali, Oksana Pogoryelova, Alexa Derksen, Sally Spendiff, Hanns Lochmuller, Paula Videira, Luigi Atzori, Pierluigi Caboni  

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