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Convergence of multiplexed immunosensors, nanotechnology, and AI for early pancreatic cancer diagnosis​on April 19, 2026 at 9:04 pm

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Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Qamar Abuhassan, Ahmed Faisal Mutee, Abdulkareem Shareef, Pareshkumar N. Pate, S. Renuka Jyothi, Gunjan Singh, Laxmidhar Maharana, Vimal Arora, Djamila Polatova, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil  

Transferability and Between Laboratory Imprecision of an LC-MS/MS-Based Reference Measurement Procedure for Apolipoproteins

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Clin Chem. 2026 Apr 18:hvag020. doi: 10.1093/clinchem/hvag020. Online ahead of print. ABSTRACT BACKGROUND: Apolipoprotein standardization in multiple calibration laboratories requires equivalent results to value assign matrix-based reference and external quality assurance materials. A multiplexed LC-MS/MS-based reference measurement procedure (RMP) has been developed for serum apolipoproteins apo(a), apoA-I, apoB, apoC-I, apoC-II, apoC-III, and apoE. This study … Read more

Mitochondrial DNA copy number in leukocytes predicts long-term survival in prostate cancerTanja Langsenlehneron April 17, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Apr 16. doi: 10.1515/cclm-2025-1464. Online ahead of print. ABSTRACT OBJECTIVES: Low mitochondrial DNA copy number (mtCN) in leukocytes is a predictor of all-cause mortality, independent of age and sex. For malignant diseases, results about the prognostic value of leukocyte mtCN have been conflicting. Aim of the present study was to … Read more

Improving clinical interpretation of serum alpha-fetoprotein in children: using continuous and discrete reference intervalsDien Minh Tranon April 17, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2026-0262. Online ahead of print. ABSTRACT OBJECTIVES: To establish discrete and continuous age-specific reference intervals for serum alpha-fetoprotein in children and to evaluate whether continuous modeling improves interpretation during early infancy, when concentrations decline rapidly. METHODS: In this prospective, cross-sectional study, serum alpha-fetoprotein was measured in 3,680 … Read more

Salivary testosterone reference intervals for adult women and menMirjam Kruijton April 17, 2026 at 10:00 am

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Clin Chem Lab Med. 2026 Apr 15. doi: 10.1515/cclm-2026-0144. Online ahead of print. ABSTRACT OBJECTIVES: Testosterone is increasingly being measured in saliva due to the ease of collection, which puts a lower burden on patients and facilitates measurement in clinical and behavioral studies. Although the robustness of measuring testosterone in saliva using immunoassays has been … Read more

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