In-vitro verification of tolerance limits for biotin interference of routine biochemistry and immunology assays​Kirsty Swallow, Graeme Wild, Ravishankar SargurImmunology Department and Protein Reference Unit, Northern General Hospital, Sheffield, UKon March 25, 2026 at 1:17 am

Annals of Clinical Biochemistry, Ahead of Print.
BackgroundBiotin is commonly used in many commercial assays. It is known that exogenous biotin can interfere with these tests, however, not all manufacturers have issued warnings or reassurances. Interference can lead to increased or decreased …

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